Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.78 |
| ▸ | MAOA | P21397 | 6/20 | 0.78 |
| ▸ | ACHE | P22303 | 2/20 | 0.57 |
| ▸ | BCHE | P06276 | 1/20 | 0.57 |
| ▸ | BACE1 | P56817 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10156171 | 0.88 | MAOA (1.00) | MAOBMAOAACHEBCHEBACE1 | |
| SCHEMBL620669 | 0.83 | MAOA (1.00) | MAOBMAOAACHEBCHEBACE1 | |
| Hydrochloric Acid SCHEMBL621934 | 0.82 | MAOA (0.98) | MAOBMAOAACHEBCHEBACE1 | |
| Hydrochloric Acid SCHEMBL620552 | 0.82 | MAOA (0.98) | MAOBMAOAACHEBCHEBACE1 | |
| SCHEMBL10156577 | 0.81 | MAOB (0.60) | MAOBMAOAACHEBCHEBACE1 | |
| SCHEMBL622835 | 0.77 | MAOA (0.56) | MAOBMAOAACHEBCHEBACE1 | |
| SCHEMBL15854517 | 0.76 | MAOA (0.78) | MAOBMAOAACHEBCHEBACE1 | |
| SCHEMBL621285 | 0.76 | MAOA (1.00) | MAOBMAOAACHEBCHEBACE1 | |
| Hydrochloric Acid SCHEMBL621870 | 0.75 | MAOA (0.98) | MAOBMAOAACHEBCHEBACE1 | |
| SCHEMBL621841 | 0.75 | MAOA (0.69) | MAOBMAOAACHEBCHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2603492-A1 | NEUROPROTECTIVE AND NEURO-RESTORATIVE IRON CHELATORS AND MONOAMINE OXIDASE INHIBITORS AND USES THEREOF | Varinel Inc. (US) | 2013-06-19 | — | — | EP | disclosed |
| WO-2012020389-A1 | NEUROPROTECTIVE AND NEURO-RESTORATIVE IRON CHELATORS AND MONOAMINE OXIDASE INHIBITORS AND USES THEREOF | VARINEL INC (US) | 2012-02-16 | — | — | WO | disclosed |