Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 13/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 13/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | CTRC | Q99895 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2401899 | 0.79 | CA12 (0.47) | F2MTNR1AMTNR1BALDH1A1TSHR | |
| SCHEMBL283756 | 0.76 | HTR7 (0.48) | HTR7ALDH1A1TSHRMAPK1KDM4E | |
| SCHEMBL4550868 | 0.74 | CA1 (0.40) | ALDH1A1TSHRKDM4EUSP2LMNA | |
| SCHEMBL1284402 | 0.73 | F2 (0.47) | F2ALDH1A1TSHRKDM4EUSP2 | |
| SCHEMBL29360890 | 0.72 | ALDH1A1 (0.43) | ALDH1A1TSHRTP53MAPK1HIF1A | |
| SCHEMBL5656552 | 0.70 | KDM4E (0.36) | ALDH1A1TSHRMAPK1HSD17B10KDM4E | |
| SCHEMBL22804712 | 0.70 | TSHR (0.38) | ALDH1A1TSHRKDM4EUSP2LMNA | |
| SCHEMBL11914192 | 0.69 | ALDH1A1 (0.40) | ALDH1A1TSHRTP53MAPK1HIF1A | |
| SCHEMBL14313675 | 0.69 | MEN1 (0.41) | ALDH1A1KDM4EUSP2LMNA | |
| SCHEMBL10157357 | 0.69 | HTR7 (0.49) | HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040968-A1 | DIAMINO HETEROCYCLIC CARBOXAMIDE COMPOUND | WATERS TECHNOLOGIES CORPORATION (US) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040968-A1 | DIAMINO HETEROCYCLIC CARBOXAMIDE COMPOUND | EML4, ALK, ERBB4 | F2 4414/4885MTNR1A 4462/4885MTNR1B 4165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.