Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 7/20 | 0.50 |
| ▸ | MMP13 | P45452 | 4/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP14 | P50281 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11829478 | 0.88 | MMP12 (0.53) | MMP12MMP13MMP2MMP9MMP14 | |
| SCHEMBL11899992 | 0.82 | PARP10 (0.48) | FFAR1 | |
| SCHEMBL17921153 | 0.78 | FDFT1 (0.49) | MMP12MMP13MMP2MMP9MMP14 | |
| SCHEMBL23849495 | 0.78 | BLM (0.46) | — | |
| SCHEMBL17921148 | 0.77 | HDAC2 (0.47) | MMP12MMP13MMP2MMP9MMP14 | |
| SCHEMBL11823337 | 0.77 | MMP12 (0.54) | MMP12MMP13MMP2MMP9MMP14 | |
| SCHEMBL5990 | 0.77 | MMP2 (0.43) | MMP12MMP13MMP2MMP9MMP14 | |
| SCHEMBL17921177 | 0.76 | HDAC2 (0.48) | MMP12MMP13MMP2MMP9MMP14 | |
| SCHEMBL11837469 | 0.76 | MMP12 (0.53) | MMP12MMP13MMP2MMP9MMP14 | |
| SCHEMBL11828178 | 0.75 | MMP12 (0.55) | MMP12MMP13MMP2MMP9MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488489-A2 | C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | Pfizer Inc. (US) | 2012-08-22 | — | — | EP | disclosed |
| WO-2011045703-A2 | C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2011-04-21 | — | — | WO | disclosed |