Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2695687 | 0.84 | ALDH1A1 (0.67) | ALDH1A1KDM4EHTTSMN1; SMN2RAB9A | |
| SCHEMBL5358931 | 0.82 | CYP2C9 (0.75) | ALDH1A1HTTCYP2C9SMN1; SMN2RAB9A | |
| SCHEMBL7672594 | 0.82 | CYP2C9 (0.75) | ALDH1A1HTTCYP2C9SMN1; SMN2RAB9A | |
| SCHEMBL10157136 | 0.81 | USP2 (0.65) | ALDH1A1KDM4EHTTCYP2C9SMN1; SMN2 | |
| SCHEMBL12707584 | 0.80 | ALDH1A1 (0.67) | ALDH1A1KDM4EHTTSMN1; SMN2RAB9A | |
| SCHEMBL48578 | 0.80 | HTT (0.64) | ALDH1A1HTTSMN1; SMN2RAB9AGAA | |
| SCHEMBL10157126 | 0.79 | HPGD (0.56) | ALDH1A1KDM4EHTTCYP2C9SMN1; SMN2 | |
| SCHEMBL2695729 | 0.79 | ALDH1A1 (0.61) | ALDH1A1KDM4EHTTSMN1; SMN2RAB9A | |
| SCHEMBL10157129 | 0.79 | MEN1 (0.59) | ALDH1A1HTTCYP2C9SMN1; SMN2RAB9A | |
| SCHEMBL774432 | 0.79 | ALDH1A1 (0.65) | ALDH1A1KDM4EHTTSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8895551-B2 | Acrylamide compounds and the use thereof | SHIONOGI & CO., LTD. (JP) | 2014-11-25 | — | — | US | disclosed |
| US-20120022069-A1 | ACRYLAMIDE COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022069-A1 | ACRYLAMIDE COMPOUNDS AND THE USE THEREOF | TRPA1, TRPV1, CACNA1B | ALDH1A1 809/4885KDM4E 4485/4885HTT 382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.