Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | FES | P07332 | 1/20 | 0.55 |
| ▸ | RET | P07949 | 1/20 | 0.55 |
| ▸ | MARK3 | P27448 | 1/20 | 0.55 |
| ▸ | TYK2 | P29597 | 1/20 | 0.55 |
| ▸ | FLT4 | P35916 | 1/20 | 0.55 |
| ▸ | SYK | P43405 | 1/20 | 0.55 |
| ▸ | CLK2 | P49760 | 1/20 | 0.55 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2698425 | 0.86 | USP2 (0.70) | USP2RECQLPKMKMT2ATHRB | |
| SCHEMBL7666539 | 0.83 | USP2 (0.55) | USP2RECQLPKMKMT2ATHRB | |
| SCHEMBL7666543 | 0.83 | USP2 (0.55) | USP2RECQLPKMKMT2ATHRB | |
| SCHEMBL7666536 | 0.83 | USP2 (0.55) | USP2RECQLPKMKMT2ATHRB | |
| SCHEMBL45843 | 0.82 | RECQL (0.70) | USP2RECQLPKMKMT2AMAPT | |
| SCHEMBL774098 | 0.81 | USP2 (0.68) | USP2RECQLPKMKMT2ATHRB | |
| SCHEMBL31321078 | 0.81 | USP2 (0.68) | USP2RECQLPKMKMT2ATHRB | |
| SCHEMBL31321074 | 0.81 | USP2 (0.68) | USP2RECQLPKMKMT2ATHRB | |
| SCHEMBL10157134 | 0.81 | ALDH1A1 (0.61) | MAPTALDH1A1HTTNPSR1CYP3A4 | |
| SCHEMBL26125902 | 0.81 | USP2 (0.63) | USP2RECQLPKMKMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10189810-B2 | Pyrazolyl-substituted pyridone compounds as serine protease inhibitors | VERSEON CORPORATION (US) | 2019-01-29 | — | — | US | disclosed |
| US-20170267656-A1 | PYRAZOLYL-SUBSTITUTED PYRIDONE COMPOUNDS AS SERINE PROTEASE INHIBITORS | VERSEON INTERNATIONAL CORPORATION | 2017-09-21 | — | — | US | disclosed |
| US-8895551-B2 | Acrylamide compounds and the use thereof | SHIONOGI & CO., LTD. (JP) | 2014-11-25 | — | — | US | disclosed |
| US-20120022069-A1 | ACRYLAMIDE COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022069-A1 | ACRYLAMIDE COMPOUNDS AND THE USE THEREOF | TRPA1, TRPV1, CACNA1B | USP2 2240/4885RECQL 673/4885PKM 4138/4885 |
| US-20170267656-A1 | PYRAZOLYL-SUBSTITUTED PYRIDONE COMPOUNDS AS SERINE PROTEASE INHIBITORS | SERPINE1, PRSS1, SPINT2 | USP2 2512/4885RECQL 1004/4885PKM 228/4885 |
| US-10189810-B2 | Pyrazolyl-substituted pyridone compounds as serine protease inhibitors | SERPINE1, PRSS1, SPINT2 | USP2 2512/4885RECQL 1004/4885PKM 228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.