SCHEMBL10158103

SCHEMBL10158103

CCCNC(=O)c1ccccc1C(=O)O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.68
TSHR P16473 1/20 0.68
KMT2A Q03164 2/20 0.61
APEX1 P27695 1/20 0.61
LMNA P02545 1/20 0.58
MAPT P10636 1/20 0.58
POLB P06746 1/20 0.56
MAPK1 P28482 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
HPGD P15428 1/20 0.54
KDM4E B2RXH2 1/20 0.54
TAAR1 Q96RJ0 1/20 0.54
NAAA Q02083 1/20 0.53
CA12 O43570 1/20 0.53
CA9 Q16790 1/20 0.53
CYP1A2 P05177 1/20 0.53
CYP2C19 P33261 1/20 0.53
ALDH1A1 P00352 2/20 0.52
GAA P10253 1/20 0.52
ALOX15 P16050 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6273378 0.89 HTT (0.86) HTTTSHRKMT2AAPEX1LMNA
SCHEMBL10889755 0.88 KMT2A (0.69) HTTTSHRKMT2AAPEX1LMNA
SCHEMBL28810855 0.88 HTT (0.77) HTTTSHRKMT2AAPEX1L3MBTL1
SCHEMBL11089466 0.86 HTT (0.75) HTTTSHRLMNAHPGDNAAA
SCHEMBL8963414 0.86 HTT (0.75) HTTTSHRLMNAHPGDNAAA
SCHEMBL23610316 0.86 HTT (0.75) HTTTSHRLMNAHPGDNAAA
SCHEMBL2638598 0.86 HTT (0.75) HTTTSHRLMNAHPGDNAAA
SCHEMBL14483849 0.86 HTT (0.75) HTTTSHRLMNAHPGDNAAA
SCHEMBL986325 0.86 HTT (0.75) HTTTSHRLMNAHPGDNAAA
SCHEMBL23610299 0.86 HTT (0.75) HTTTSHRLMNAHPGDNAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3377492-B1 CATALYST FOR THE PREPARATION OF POLYURETHANES BASF SE (DE) 2022-08-31 EP disclosed
CN-108368109-B Catalyst for preparing polyurethane 巴斯夫欧洲公司 2021-11-23 CN disclosed
US-11021560-B2 Catalyst for the preparation of polyurethanes BASF SE (DE) 2021-06-01 US disclosed
US-11021560-B2 Catalyst for the preparation of polyurethanes BASF SE (DE) 2021-06-01 US disclosed
US-20200172652-A9 CATALYST FOR THE PREPARATION OF POLYURETHANES BASF SE (DE) 2020-06-04 US disclosed
US-20200172652-A9 CATALYST FOR THE PREPARATION OF POLYURETHANES BASF SE (DE) 2020-06-04 US disclosed
US-20180327534-A1 CATALYST FOR THE PREPARATION OF POLYURETHANES BASF SE (CH) 2018-11-15 US disclosed
EP-3377492-A1 CATALYST FOR THE PREPARATION OF POLYURETHANES BASF SE (DE) 2018-09-26 EP disclosed
CN-108368109-A It is used to prepare the catalyst of polyurethane 巴斯夫欧洲公司 2018-08-03 CN disclosed
US-20130190491-A1 INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION GILEAD SCIENCES, INC. (US) 2013-07-25 US disclosed
US-4160095-A PROSTAGLANDINS; ANTIINFLAMMATORY AGENTS THE UPJOHN COMPANY (US) 1979-07-03 US disclosed
US-4157441-A PROSTAGLANDINS, ANTIINFLAMMATORY AGENTS THE UPJOHN COMPANY (US) 1979-06-05 US disclosed
US-4151351-A PROSTAGLANDINS, ANTIINFLAMMATORY THE UPJOHN COMPANY (US) 1979-04-24 US disclosed
US-4131738-A 6-Hydroxy-PGE1 compounds THE UPJOHN COMPANY (US) 1978-12-26 US disclosed
US-4128713-A 6,7-Didehydro-PGI1 compounds THE UPJOHN COMPANY (US) 1978-12-05 US disclosed
US-4126744-A PROSTACYCLIN, MUSCLE STIMULANTS, PLATELET AGGREGATION INHIBITORS THE UPJOHN COMPANY (US) 1978-11-21 US disclosed
US-4112224-A PROSTAGLANDIN THE UPJOHN COMPANY (US) 1978-09-05 US disclosed
US-4109082-A PROSTACYCLIN ANALOGS; SMOOTH MUSCLE STIMULATORS THE UPJOHN COMPANY (US) 1978-08-22 US disclosed
US-4100192-A Inter-phenylene-PG amides THE UPJOHN COMPANY (US) 1978-07-11 US disclosed
US-4097489-A PROSTAGLANDINS THE UPJOHN COMPANY (US) 1978-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180327534-A1 CATALYST FOR THE PREPARATION OF POLYURETHANES PUF60, UNG, UMPS HTT 3621/4885TSHR 4723/4885KMT2A 957/4885
US-20200172652-A9 CATALYST FOR THE PREPARATION OF POLYURETHANES PUF60, UNG, UMPS HTT 3621/4885TSHR 4723/4885KMT2A 957/4885
US-11021560-B2 Catalyst for the preparation of polyurethanes PUF60, UNG, UMPS HTT 3621/4885TSHR 4723/4885KMT2A 957/4885
US-20130190491-A1 INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION RTF2, REV1, RTF1 HTT 3421/4885TSHR 2846/4885KMT2A 2634/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.