Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21344787 | 0.94 | ALDH1A1 (0.65) | ALDH1A1SLC1A3SLC1A2SLC1A1KMT2A | |
| SCHEMBL9359510 | 0.89 | ALDH1A1 (0.59) | ALDH1A1SLC1A3SLC1A2SLC1A1KMT2A | |
| SCHEMBL9194035 | 0.89 | ALDH1A1 (0.51) | ALDH1A1CA12CA1CA2CA3 | |
| SCHEMBL16854594 | 0.85 | TSHR (0.44) | ALDH1A1CA12CA1CA2CA3 | |
| SCHEMBL10158689 | 0.85 | ALDH1A1 (0.43) | ALDH1A1CA12CA1CA2CA3 | |
| SCHEMBL10158691 | 0.84 | ALDH1A1 (0.42) | ALDH1A1CA12CA1CA2CA3 | |
| SCHEMBL9191601 | 0.83 | ALDH1A1 (0.51) | ALDH1A1CA12CA1CA2CA3 | |
| SCHEMBL10158705 | 0.82 | ALDH1A1 (0.40) | ALDH1A1CA12CA1CA2CA3 | |
| SCHEMBL29344722 | 0.81 | ALDH1A1 (0.53) | ALDH1A1SLC1A1MAPK1L3MBTL1TDP1 | |
| SCHEMBL5664039 | 0.81 | ALDH1A1 (0.65) | ALDH1A1SLC1A3SLC1A2SLC1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160169864-A1 | FIBER COATED NANOPORES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-06-16 | — | — | US | disclosed |
| US-20130195954-A1 | FILMS AND PARTICLES | THE TRUSTEES OF THE BOSTON UNIVERSITY (US) | 2013-08-01 | — | — | US | disclosed |
| US-8338492-B2 | Films and particles | THE TRUSTEES OF THE BOSTON UNIVERSITY (US) | 2012-12-25 | — | — | US | disclosed |
| US-8334324-B2 | Films and particles | THE TRUSTEES OF THE BOSTON UNIVERSITY (US) | 2012-12-18 | — | — | US | disclosed |
| US-20120107365-A1 | FILMS AND PARTICLES | THE TRUSTEES OF THE BOSTON UNIVERSITY (US) | 2012-05-03 | — | — | US | disclosed |
| US-20110152305-A1 | FILMS AND PARTICLES | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152305-A1 | FILMS AND PARTICLES | APOB, PGF, ACTB | ALDH1A1 2505/4885CA12 1547/4885CA1 3355/4885 |
| US-20130195954-A1 | FILMS AND PARTICLES | APOB, PGF, ACTB | ALDH1A1 2505/4885CA12 1547/4885CA1 3355/4885 |
| US-20120107365-A1 | FILMS AND PARTICLES | APOB, PGF, ACTB | ALDH1A1 2505/4885CA12 1547/4885CA1 3355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.