⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL27847366 | 0.94 | ALDH1A1 (0.33) | — | |
| Chloromethane SCHEMBL8972580 | 0.94 | ALDH1A1 (0.40) | — | |
| Acrylic Acid SCHEMBL11402097 | 0.87 | LMNA (0.50) | — | |
| Acrylamide SCHEMBL27634952 | 0.83 | ALDH1A1 (0.50) | — | |
| SCHEMBL4242460 | 0.80 | — | — | |
| SCHEMBL31274247 | 0.79 | TDP1 (0.39) | — | |
| SCHEMBL2444763 | 0.76 | ALDH1A1 (0.39) | — | |
| SCHEMBL25527805 | 0.75 | — | — | |
| SCHEMBL982870 | 0.73 | TSHR (0.32) | — | |
| SCHEMBL3686946 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 312 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240376106-A1 | PROCESS OF PREPARING A PD-1/PD-L1 INHIBITOR | INCYTE CORPORATION | 2024-11-14 | — | — | US | claimed |
| CN-115572257-B | Synthesis method of pyridone compound | 江西帝劢药业有限公司 | 2024-07-09 | — | — | CN | claimed |
| CN-117603072-A | 2-difluoro acetyl-3-dimethylamino acrylic acid compound, and preparation method and application thereof | 安徽泓泽新材料科技有限公司 | 2024-02-27 | — | — | CN | claimed |
| CN-117430602-A | Method for preparing 6-halogeno-4-hydroxy [1,5] naphthyridine-3-formate and derivative thereof | 爱斯特（成都）生物制药股份有限公司 | 2024-01-23 | — | — | CN | claimed |
| US-11780836-B2 | Process of preparing a PD-1/PD-L1 inhibitor | INCYTE CORPORATION (US) | 2023-10-10 | — | — | US | claimed |
| EP-3490622-B1 | METHODS AND COMPOSITIONS FOR WOUND HEALING | IMBED BIOSCIENCES INC (US) | 2023-09-06 | — | — | EP | claimed |
| CN-116425720-A | Preparation method of delafloxacin meglumine | 广东东阳光药业有限公司 | 2023-07-14 | — | — | CN | claimed |
| CN-115572257-A | Synthesis method of pyridone compound | 江西帝劢药业有限公司 | 2023-01-06 | — | — | CN | claimed |
| CN-115135307-A | Carrier for cell delivery | 株式会社ITO | 2022-09-30 | — | — | CN | claimed |
| US-20220144830-A1 | PROCESS OF PREPARING A PD-1/PD-L1 INHIBITOR | INCYTE CORPORATION | 2022-05-12 | — | — | US | claimed |
| EP-0826697-A2 | Polymerization processes and resin particles formed thereby | XEROX CORPORATION (US) | 1998-03-04 | — | — | EP | claimed |
| EP-0759039-A4 | — | — | 1997-03-26 | — | — | EP | claimed |
| EP-0759039-A1 | ACRYLATE POLYMERIZATION PROCESSES | XEROX CORPORATION (US) | 1997-02-26 | — | — | EP | claimed |
| EP-0735064-A1 | Process for the preparation of branched polymers | XEROX CORPORATION (US) | 1996-10-02 | — | — | EP | claimed |
| EP-0720990-A2 | Radical polymerization process | XEROX CORPORATION (US) | 1996-07-10 | — | — | EP | claimed |
| US-5530079-A | HEATING A MIXTURE OF FREE RADICAL INITIATOR, STABLE FREE RADICAL AGENT AND POLYMERIZABLE MONOMER; RESULTING POLYMER IS COMPRISED OF A COVALENTLY BOUND FREE RADICAL INITIATOR AT ONE END AND A BOUND STABLE FREE RADICAL AT OTHER | XEROX CORPORATION (US) | 1996-06-25 | — | — | US | claimed |
| WO-1995031484-A1 | ACRYLATE POLYMERIZATION PROCESSES | XEROX CORPORATION (US) | 1995-11-23 | — | — | WO | claimed |
| US-5412047-A | Molecular weight control | XEROX CORPORATION (US) | 1995-05-02 | — | — | US | claimed |
| US-4666617-A | ALKYLAMINO-ACRYLATE POLYMERS, FATTY ACID, ALKYL PHOSPHATES | NIPPON KOKAN KABUSHIKI KAISHA (JP) | 1987-05-19 | — | — | US | claimed |
| US-4256782-A | IRRADIATING A POLYMERIZABLE COMPOUND ON THE SURFACE | KANSAI PAINT CO., LTD. (JP) | 1981-03-17 | — | — | US | claimed |