Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 11/20 | 0.64 |
| ▸ | ABL1 | P00519 | 3/20 | 0.52 |
| ▸ | BCR | P11274 | 3/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1013990 | 0.79 | TRPV1 (0.62) | TRPV1ABL1BCRFAAHTP53 | |
| SCHEMBL4620674 | 0.78 | TRPV1 (1.00) | TRPV1ABL1BCRFAAHTP53 | |
| Hydrochloric Acid SCHEMBL4622097 | 0.77 | TRPV1 (0.98) | TRPV1ABL1BCRFAAHTP53 | |
| SCHEMBL1013844 | 0.76 | TRPV1 (0.65) | TRPV1ABL1BCRFAAHTP53 | |
| SCHEMBL1014056 | 0.75 | TRPV1 (0.72) | TRPV1ABL1BCRFAAHTP53 | |
| SCHEMBL1012994 | 0.75 | TRPV1 (0.72) | TRPV1ABL1BCRFAAHTP53 | |
| SCHEMBL15534259 | 0.75 | TRPV1 (0.57) | TRPV1ABL1BCRFAAH | |
| Hydrochloric Acid SCHEMBL1012455 | 0.74 | TRPV1 (0.71) | TRPV1ABL1BCRFAAHTP53 | |
| Hydrochloric Acid SCHEMBL1011887 | 0.74 | TRPV1 (0.71) | TRPV1ABL1BCRFAAHTP53 | |
| SCHEMBL15534267 | 0.74 | TRPV1 (0.56) | TRPV1ABL1BCRFAAHTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1542692-B1 | AMINOPYRIMIDINE DERIVATIVES FOR USE AS VANILLOID RECEPTOR LIGANDS FOR THE TREATMENT OF PAIN | AMGEN INC (US) | 2011-01-05 | — | — | EP | claimed |