SCHEMBL10160130

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1095578	0.83	TDP1 (0.54)	TDP1KMT2AMAPK1MAPTMEN1
	SCHEMBL2740822	0.82	CES1 (0.44)	TDP1KMT2AMAPK1MAPTMEN1
	SCHEMBL562504	0.79	MAPK1 (0.61)	TDP1KMT2AMAPK1MAPTMEN1
	SCHEMBL1128350	0.79	TDP1 (0.50)	TDP1KMT2AMAPK1MAPTMEN1
	SCHEMBL4110305	0.79	KMT2A (0.50)	TDP1KMT2AMAPK1MAPTMEN1
	SCHEMBL8855000	0.76	MAPT (0.47)	TDP1KMT2AMAPK1MAPTMEN1
	Perchlorate SCHEMBL9003671	0.76	TDP1 (0.47)	TDP1KMT2AMAPK1MAPTMEN1
	SCHEMBL686321	0.76	KMT2A (0.56)	TDP1KMT2AMAPK1MAPTMEN1
	SCHEMBL565176	0.76	MAPT (0.56)	TDP1KMT2AMAPK1MAPTMEN1
	Bromide SCHEMBL394250	0.74	KMT2A (0.54)	TDP1KMT2AMAPK1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.