SCHEMBL10161141

SCHEMBL10161141

CCc1ccc2c(c1)c1cc(CC)ccc1n2-c1ccc(N(c2ccccc2)c2ccc(-c3ccc4c(-c5ccccc5)c5ccccc5c(-c5ccccc5)c4c3)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSPO P30536 3/20 0.37
PGR P06401 1/20 0.34
RORA P35398 1/20 0.34
RORC P51449 1/20 0.34
RORB Q92753 1/20 0.34
PTGES O14684 1/20 0.34
MAPKAPK2 P49137 1/20 0.32
RXRA P19793 1/20 0.32
RXRB P28702 1/20 0.32
MAPT P10636 2/20 0.32
KHK P50053 1/20 0.32
BCL2 P10415 1/20 0.32
PLA2G4A P47712 1/20 0.31
AKR1C4 P17516 1/20 0.31
AKR1C3 P42330 1/20 0.31
AKR1C2 P52895 1/20 0.31
AKR1C1 Q04828 1/20 0.31
DNM1 Q05193 1/20 0.31
KIF11 P52732 1/20 0.31
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL262492 0.98 TSPO (0.38) TSPOPGRRORARORCRORB
SCHEMBL2613950 0.96 TSPO (0.36) TSPOPGRRORARORCRORB
SCHEMBL14029412 0.96 TSPO (0.38) TSPOPGRRORARORCRORB
SCHEMBL13295045 0.93 PGR (0.38) TSPOPGRRORARORCRORB
SCHEMBL10175858 0.92 TSPO (0.36) TSPOPGRRORARORCRORB
SCHEMBL19296443 0.91 TSPO (0.42) TSPOPGRRORARORCRORB
SCHEMBL262827 0.91 TSPO (0.40) TSPOPGRRORARORCRORB
SCHEMBL2613622 0.91 TSPO (0.38) TSPOMAPTACHEKDM4EATM
SCHEMBL10160986 0.91 TSPO (0.38) TSPOMAPTACHEKDM4EATM
SCHEMBL13295047 0.90 AKR1C4 (0.34) PGRRORARORCRORBPTGES

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8288012-B2 Anthracene derivatives and light-emitting devices using the anthracene derivatives SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-10-16 US disclosed
US-8288012-B2 Anthracene derivatives and light-emitting devices using the anthracene derivatives SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-10-16 US disclosed
US-20120211728-A1 Light-Emitting Element, Light-Emitting Device, and Electronic Appliance SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-08-23 US disclosed
US-20120211728-A1 Light-Emitting Element, Light-Emitting Device, and Electronic Appliance SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-08-23 US disclosed
EP-2031036-B1 Light-emitting element, light-emitting device, and electronic appliance SEMICONDUCTOR ENERGY LAB (JP) 2012-06-27 EP disclosed
US-8101289-B2 Light-emitting element, light-emitting device, and electronic appliance SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-01-24 US disclosed
US-8101289-B2 Light-emitting element, light-emitting device, and electronic appliance SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-01-24 US disclosed
US-20090058278-A1 Light-Emitting Element, Light-Emitting Device, and Electronic Appliance SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-03-05 US disclosed
US-20090058278-A1 Light-Emitting Element, Light-Emitting Device, and Electronic Appliance SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-03-05 US disclosed
EP-2031036-A1 Light-emitting element, light-emitting device, and electronic appliance SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-03-04 EP disclosed
US-20090004506-A1 Anthracene Derivatives and Light-Emitting Devices Using the Anthracene Derivatives SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-01-01 US disclosed
US-20090004506-A1 Anthracene Derivatives and Light-Emitting Devices Using the Anthracene Derivatives SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-01-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090004506-A1 Anthracene Derivatives and Light-Emitting Devices Using the Anthracene Derivatives CRY1, CYP1A1, GLB1 TSPO 2918/4885PGR 2475/4885RORA 2084/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.