Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10161708 | 0.91 | RAD52 (0.30) | RAD52 | |
| SCHEMBL10163075 | 0.89 | TUBB4A (0.33) | — | |
| SCHEMBL10163082 | 0.88 | POLB (0.35) | — | |
| SCHEMBL10163076 | 0.86 | GAA (0.34) | RAD52 | |
| SCHEMBL10163077 | 0.85 | TUBB4A (0.33) | — | |
| SCHEMBL10163129 | 0.82 | RAD52 (0.35) | RAD52 | |
| SCHEMBL10161707 | 0.82 | ALDH1A1 (0.32) | RAD52 | |
| SCHEMBL10161703 | 0.79 | ALDH1A1 (0.31) | — | |
| SCHEMBL13284349 | 0.75 | RAC1 (0.53) | RAD52 | |
| SCHEMBL10132640 | 0.74 | RAC1 (0.44) | RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120022061-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | RUGTERS, THE STATE UNIVERSITY OF NEW JERSEY | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022061-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | CCNT1, XPO4, XDH | RAD52 768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.