SCHEMBL101627

SCHEMBL101627

Fc1cc[c]cc1C(F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28052047 0.82
SCHEMBL147600 0.81 KIF11 (0.36) KIF11
SCHEMBL146460 0.80 AR (0.31)
SCHEMBL6761318 0.79 CA2 (0.30)
SCHEMBL14483362 0.78 GLA (0.38)
SCHEMBL27618380 0.76
SCHEMBL145873 0.76 AR (0.32)
SCHEMBL15018296 0.76
SCHEMBL18706010 0.76
SCHEMBL17965406 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2319 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117143099-B Evodiamine derivative, preparation method thereof and application of evodiamine derivative as PGAM1 inhibitor 陕西中医药大学 2024-07-09 CN claimed
EP-3893645-B1 SUBSTITUTED ARYLMETHYLUREAS AND HETEROARYLMETHYLUREAS, ANALOGUES THEREOF, AND METHODS USING SAME ARBUTUS BIOPHARMA CORP (CA) 2024-04-17 EP claimed
EP-3750894-B1 UREA-SUBSTITUTED AROMATIC RING-LINKED DIOXAZOLINE COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF BEIJING SCITECH MQ PHARMACEUTICALS LTD (CN) 2024-04-03 EP claimed
US-11926758-B2 Polytriazole coating materials for metal substrates SAUDI ARABIAN OIL COMPANY (SA) 2024-03-12 US claimed
WO-2024012496-A1 CANNABINOID RECEPTOR COMPOUND AND USE THEREOF 长春金赛药业有限责任公司 2024-01-18 WO claimed
US-20230381142-A1 ANTILEISHMANIAL COMPOUNDS, COMPOSITIONS AND USE THEREOF TRUSTEES OF BOSTON UNIVERSITY (US) 2023-11-30 US claimed
WO-2023227734-A1 FLAVIVIRUS INHIBITORS IRBM S.P.A. (IT) 2023-11-30 WO claimed
WO-2023230217-A1 ANTILEISHMANIAL COMPOUNDS, COMPOSITIONS AND USE THEREOF TRUSTEES OF BOSTON UNIVERSITY (US) 2023-11-30 WO claimed
EP-3590941-B1 UREA-SUBSTITUTED AROMATIC RING-LINKED DIOXANE-QUINAZOLINE AND -LINKED DIOXANE-QUINOLINE COMPOUNDS, PREPARATION METHOD THEREFOR AND USE THEREOF BEIJING SCITECH MQ PHARMACEUTICALS LTD (CN) 2023-11-22 EP claimed
EP-3901147-B1 ACYLAMINO BRIDGED HETEROCYCLIC COMPOUND, AND COMPOSITION AND APPLICATION THEREOF BEIJING SCITECH MQ PHARMACEUTICALS LTD (CN) 2023-11-22 EP claimed
EP-0193303-B1 ALKENE, ALKYNE OR CYCLOALKYLENE DERIVATIVES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-10-23 EP claimed
US-5045566-A Phenyl or naphthyl substituted ICI AMERICAS INC. (US) 1991-09-03 US claimed
US-4873329-A ANTIANDROGENS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-10-10 US claimed
US-4859228-A Novel 5-aminomethylene-2,4-imidazolidinediones and 5-aminomethylene-2-thionoimidazolidine-4-ones ICI AMERICAS INC (US) 1989-08-22 US claimed
US-4845119-A ANTIAANDROGENS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-07-04 US claimed
EP-0300882-A2 Novel 5-Aminomethylene-2,4-imidazolidinediones and 5-aminomethylene-2-thionoimidazolidine-4-ones ICI AMERICAS INC. (US) 1989-01-25 EP claimed
EP-0193303-A2 Alkene, alkyne or cycloalkylene derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-09-03 EP claimed
EP-0154528-A2 Alkene, alkyne or cycloalkylene derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-09-11 EP claimed
EP-0017976-A2 Process for preparing imidazole derivatives F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1980-10-29 EP claimed
US-4153617-A Anorexic chromans BEECHAM GROUP LIMITED (GB) 1979-05-08 US claimed