Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | ACACB | O00763 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.42 |
| ▸ | MTOR | P42345 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12603967 | 0.84 | ALDH1A1 (0.64) | ALDH1A1CYP1A2ACACBRAB9ATLR8 | |
| SCHEMBL23781564 | 0.83 | ALDH1A1 (0.71) | ALDH1A1CYP1A2ACACBPDGFRBPDGFRA | |
| SCHEMBL372200 | 0.83 | ALDH1A1 (1.00) | ALDH1A1CYP1A2ACACBPDGFRBPDGFRA | |
| SCHEMBL14294117 | 0.83 | ALDH1A1 (0.62) | ALDH1A1CYP1A2ACACBPDGFRBPDGFRA | |
| SCHEMBL10130641 | 0.83 | ALDH1A1 (0.66) | ALDH1A1CYP1A2ACACBPDGFRBPDGFRA | |
| SCHEMBL14453818 | 0.81 | ALDH1A1 (0.64) | ALDH1A1CYP1A2ACACBPDGFRBPDGFRA | |
| SCHEMBL7214768 | 0.81 | ALDH1A1 (0.63) | ALDH1A1CYP1A2ACACBPDGFRBPDGFRA | |
| SCHEMBL8907669 | 0.81 | ALDH1A1 (0.77) | ALDH1A1CYP1A2ACACBPDGFRBPDGFRA | |
| SCHEMBL6881031 | 0.80 | ALDH1A1 (0.66) | ALDH1A1CYP1A2ACACBPDGFRBPDGFRA | |
| SCHEMBL7544088 | 0.80 | ALDH1A1 (0.57) | ALDH1A1CYP1A2ACACBPDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108276319-B | A kind of thio-compounds and its application | 广州同隽医药科技有限公司 | 2019-11-12 | — | — | CN | disclosed |
| CN-108546242-B | A kind of dithiocarbamates compound and its application | 广州同隽医药科技有限公司 | 2019-11-12 | — | — | CN | disclosed |
| CN-108546242-A | A kind of dithiocarbamates compound and its application | 广州同隽医药科技有限公司 | 2018-09-18 | — | — | CN | disclosed |
| CN-108276319-A | A kind of novel thio-compounds and its application | 广州同隽医药科技有限公司 | 2018-07-13 | — | — | CN | disclosed |
| US-20140135485-A1 | 6-11 BICYCLIC KETOLIDE DERIVATIVES | ENANTA PHARMACEUTICALS, INC. (US) | 2014-05-15 | — | — | US | disclosed |
| CN-102504014-A | Peptidomimetic protease inhibitors | LILLY CO ELI | 2012-06-20 | — | — | CN | disclosed |
| US-20120035352-A1 | 6-11 Bicyclic Ketolide Derivatives | OR YAT SUN (US) | 2012-02-09 | — | — | US | disclosed |
| CN-101437828-A | MGLUR1 antagonists as therapeutic agents | SCHERING CORP (US) | 2009-05-20 | — | — | CN | disclosed |
| CN-101309925-A | Fused tetracyclic mglur1 antagonists as therapeutic agents | SCHERING CORP (US) | 2008-11-19 | — | — | CN | disclosed |
| CN-101291937-A | Fused tricyclic mgiur1 antagonists as therapeutic agents | SCHERING CORP (US) | 2008-10-22 | — | — | CN | disclosed |
| US-7407942-B2 | 3,6-bridged 9,12-oxolides | EMATA PHARMACEUTICALS, INC (US) | 2008-08-05 | — | — | US | disclosed |
| WO-2008061189-A1 | C-9 ALKENYLIDINE BRIDGED MACROLIDES | ENANTA PHARMACEUTICALS, INC. (US) | 2008-05-22 | — | — | WO | disclosed |
| WO-2008014221-A2 | BRIDGED CARBAMATE MACROLIDES | ENANTA PHARMACEUTICALS, INC. (US) | 2008-01-31 | — | — | WO | disclosed |
| CN-101061097-A | Novel gamma secretase inhibitors | SCHERING CORP (US) | 2007-10-24 | — | — | CN | disclosed |
| US-20070244160-A1 | 6-11 Bicyclic Ketolide Derivatives | OR YAT SUN | 2007-10-18 | — | — | US | disclosed |
| US-20070232554-A1 | 3,6-Bridged 9,12-oxolides | ENATA PHARMACEUTICALS, INC. | 2007-10-04 | — | — | US | disclosed |
| US-7247617-B2 | Sixteen-member macrolide antiinfective agents | KOSAN BIOSCIENCES INCORPORATED (US) | 2007-07-24 | — | — | US | disclosed |
| CN-101001862-A | Tricyclic compounds and their use as MGLUR1 antagonists | SCHERING CORP (US) | 2007-07-18 | — | — | CN | disclosed |
| CN-1950358-A | Novel gamma secretase inhibitors | SCHERING CORP (US) | 2007-04-18 | — | — | CN | disclosed |
| CN-1820010-A | Bridged n-arylsulfonylpiperidines as gamma-secretase inhibitors | SCHERING CORP (US) | 2006-08-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140135485-A1 | 6-11 BICYCLIC KETOLIDE DERIVATIVES | AKR1C2, AKR1C3, AKR1C1 | ALDH1A1 452/4885CYP1A2 104/4885ACACB 428/4885 |
| US-20120035352-A1 | 6-11 Bicyclic Ketolide Derivatives | AKR1C2, AKR1C3, AKR1C1 | ALDH1A1 452/4885CYP1A2 104/4885ACACB 428/4885 |
| US-20070244160-A1 | 6-11 Bicyclic Ketolide Derivatives | AKR1C2, AKR1C3, AKR1C1 | ALDH1A1 452/4885CYP1A2 104/4885ACACB 428/4885 |
| US-20070232554-A1 | 3,6-Bridged 9,12-oxolides | CYP2C9, CYP2C19, CYP2D6 | ALDH1A1 353/4885CYP1A2 38/4885ACACB 1676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.