Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18253193 | 0.84 | ALDH1A1 (0.58) | ALDH1A1CYP1A2ACACBPDGFRBPDGFRA | |
| SCHEMBL18253192 | 0.83 | ALDH1A1 (0.65) | ALDH1A1CYP1A2ACACBPDGFRBPDGFRA | |
| SCHEMBL27614825 | 0.82 | ALDH1A1 (0.59) | ALDH1A1CYP1A2ACACBPDGFRBPDGFRA | |
| SCHEMBL547195 | 0.82 | ALDH1A1 (0.59) | ALDH1A1CYP1A2ACACBPDGFRBPDGFRA | |
| SCHEMBL4818276 | 0.81 | ALDH1A1 (0.63) | ALDH1A1CYP1A2ACACBPDGFRBPDGFRA | |
| SCHEMBL15112998 | 0.81 | ALDH1A1 (0.58) | ALDH1A1CYP1A2ACACBPDGFRBPDGFRA | |
| SCHEMBL10162702 | 0.81 | ALDH1A1 (0.71) | ALDH1A1CYP1A2ACACBPDGFRBPDGFRA | |
| SCHEMBL3061440 | 0.81 | ALDH1A1 (0.58) | ALDH1A1CYP1A2ACACBPDGFRBPDGFRA | |
| SCHEMBL11300052 | 0.78 | ALDH1A1 (0.55) | ALDH1A1CYP1A2ACACBPDGFRBPDGFRA | |
| SCHEMBL23781564 | 0.77 | ALDH1A1 (0.71) | ALDH1A1CYP1A2ACACBPDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1373767-A | Ketolide antibacterials | ORTHO MCNEIL PHARM INC (US) | 2002-10-09 | — | — | CN | claimed |
| EP-1506214-B1 | 6-11 BICYCLIC KETOLIDE DERIVATIVES | ENANTA PHARM INC (US) | 2010-01-20 | — | — | EP | disclosed |
| EP-1272500-A2 | PROCESS FOR PREPARING 6-O-ALKENYL-SUBSITUTED ERYTHROMYCIN DERIVATIVES | Abbott Laboratories (US) | 2003-01-08 | — | — | EP | disclosed |
| EP-1192139-A1 | PREPARATION OF QUINOLINE-SUBSTITUTED CARBONATE AND CARBAMATE DERIVATIVES | Abbott Laboratories (US) | 2002-04-03 | — | — | EP | disclosed |
| WO-2001000582-A1 | PREPARATION OF QUINOLINE-SUBSTITUTED CARBONATE AND CARBAMATE DERIVATIVES | ABBOTT LABORATORIES (US) | 2001-01-04 | — | — | WO | disclosed |
| WO-2000078773-A2 | PROCESS FOR PREPARING 6-O-ALKENYL-SUBSTITUTED ERYTHROMYCIN DERIV ATIVES | ABBOTT LABORATORIES (US) | 2000-12-28 | — | — | WO | disclosed |