⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27990354 | 0.97 | TSHR (0.46) | — | |
| SCHEMBL5586119 | 0.97 | — | — | |
| SCHEMBL5586096 | 0.97 | TSHR (0.46) | — | |
| SCHEMBL27819007 | 0.97 | TSHR (0.46) | — | |
| SCHEMBL2831677 | 0.92 | — | — | |
| SCHEMBL2807187 | 0.79 | — | — | |
| SCHEMBL8542086 | 0.77 | TSHR (0.41) | — | |
| SCHEMBL24175767 | 0.75 | LMNA (0.43) | — | |
| SCHEMBL291330 | 0.74 | — | — | |
| SCHEMBL3264646 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269185-A1 | Administering an oxygen scavenger; superoxidase dismutase minetic | ACTIVBIOTICS (US) | 2008-10-30 | — | — | US | claimed |
| CN-104870515-B | Sheet-like epoxy resin composition, method for producing organic EL device using same, organic EL device, and organic EL display panel | 三井化学株式会社 | 2017-07-07 | — | — | CN | disclosed |
| CN-103636286-B | Surface sealant for optical semiconductor, method for manufacturing organic EL device using same, organic EL device, and organic EL display panel | 三井化学株式会社 | 2017-02-15 | — | — | CN | disclosed |
| US-RE45670-E1 | Aryl carbonyl derivatives as therapeutic agents | NOVO NORDISK A/S (DK) | 2015-09-15 | — | — | US | disclosed |
| CN-104870515-A | Sheet-like epoxy resin composition, method for producing organic EL device using same, organic EL device, and organic EL display panel | MITSU CHEMICALS INC | 2015-08-26 | — | — | CN | disclosed |
| EP-1531815-B1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK AS (DK) | 2014-09-24 | — | — | EP | disclosed |
| CN-101130526-B | Aryl carbonyl derivatives as therapeutic agents | NOVO NORDISK AS | 2013-07-10 | — | — | CN | disclosed |
| EP-2471533-A1 | Aryl carbonyl derivatives as therapeutic agents | Novo Nordisk A/S (DK) | 2012-07-04 | — | — | EP | disclosed |
| US-20110301158-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2011-12-08 | — | — | US | disclosed |
| US-8063081-B2 | N-(2-Phenoxyphenyl)-N'-(thiazol-2-yl)urea; glucokinase inhibitor; antidiabetic, hypoglycemic agent; activators of glucokinase | NOVO NORDISK A/S (DK) | 2011-11-22 | — | — | US | disclosed |
| US-20060183783-A1 | Aryl carbonyl derivatives as therapeutic agents | VTV THERAPEUTICS LLC | 2006-08-17 | — | — | US | disclosed |
| EP-1524308-B1 | Polymerisable Cinnamates with lateral substitution | MERCK PATENT GMBH (DE) | 2006-07-26 | — | — | EP | disclosed |
| US-20050227021-A1 | Polymerisable cinnamates with lateral substitution | MERCK PATENT GMBH (DE) | 2005-10-13 | — | — | US | disclosed |
| CN-1678311-A | Arylcarbonyl derivatives useful as therapeutic agents | NOVO NORDISK AS (DK) | 2005-10-05 | — | — | CN | disclosed |
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| EP-1524308-A1 | Polymerisable Cinnamates with lateral substitution | MERCK PATENT GmbH (DE) | 2005-04-20 | — | — | EP | disclosed |
| US-20040122235-A1 | Aryl carbonyl derivatives as therapeutic agents | VTV THERAPEUTICS LLC | 2004-06-24 | — | — | US | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |
| EP-0295654-B1 | FAST-CRYSTALLIZING POLYESTER COMPOSITIONS | MONTEFIBRE S.p.A. (IT) | 1993-09-08 | — | — | EP | disclosed |
| US-4886847-A | Fast-crystallizing polyester compositions | MONTEFIBRE S.P.A. (IT) | 1989-12-12 | — | — | US | disclosed |