⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5586096 | 1.00 | TSHR (0.46) | — | |
| SCHEMBL27990354 | 1.00 | TSHR (0.46) | — | |
| SCHEMBL27819007 | 1.00 | TSHR (0.46) | — | |
| SCHEMBL1016347 | 0.97 | — | — | |
| SCHEMBL2831677 | 0.89 | — | — | |
| SCHEMBL24175767 | 0.78 | LMNA (0.43) | — | |
| SCHEMBL2807187 | 0.77 | — | — | |
| SCHEMBL292061 | 0.76 | TSHR (0.44) | — | |
| SCHEMBL8378823 | 0.76 | TSHR (0.44) | — | |
| SCHEMBL8374781 | 0.76 | TSHR (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11203670-B2 | Bissilylamino group-containing organic polysilazane compound, method for producing same, and composition containing same and cured product | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2021-12-21 | — | — | US | disclosed |
| US-20200332070-A1 | BISSILYLAMINO GROUP-CONTAINING ORGANIC POLYSILAZANE COMPOUND, METHOD FOR PRODUCING SAME, AND COMPOSITION CONTAINING SAME AND CURED PRODUCT | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2020-10-22 | — | — | US | disclosed |
| US-7294369-B2 | Polymerisable cinnamates with lateral substitution | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2007-11-13 | — | — | US | disclosed |
| EP-1524308-B1 | Polymerisable Cinnamates with lateral substitution | MERCK PATENT GMBH (DE) | 2006-07-26 | — | — | EP | disclosed |
| US-20050227021-A1 | Polymerisable cinnamates with lateral substitution | MERCK PATENT GMBH (DE) | 2005-10-13 | — | — | US | disclosed |
| EP-1524308-A1 | Polymerisable Cinnamates with lateral substitution | MERCK PATENT GmbH (DE) | 2005-04-20 | — | — | EP | disclosed |