Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19525864 | 0.86 | POLB (0.35) | POLBNPC1RAB9AMEN1KMT2A | |
| SCHEMBL192955 | 0.86 | POLB (0.35) | POLBNPC1RAB9AMEN1KMT2A | |
| SCHEMBL564213 | 0.86 | POLB (0.35) | POLBMAPTGAANPC1RAB9A | |
| SCHEMBL193085 | 0.84 | POLB (0.38) | POLBMAPTGAANPC1RAB9A | |
| SCHEMBL19525865 | 0.84 | POLB (0.38) | POLBMAPTGAANPC1RAB9A | |
| SCHEMBL192351 | 0.81 | POLB (0.37) | POLBRIPK1MAPTGAANPC1 | |
| SCHEMBL19525866 | 0.81 | POLB (0.37) | POLBRIPK1MAPTGAANPC1 | |
| SCHEMBL19270341 | 0.78 | TSHR (0.50) | RIPK1MAPTPPARGPPARATSHR | |
| SCHEMBL2740662 | 0.72 | TEAD1 (0.35) | POLBMAPTGAAALDH1A1HPGD | |
| SCHEMBL12305010 | 0.72 | TEAD1 (0.35) | POLBMAPTGAAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9062040-B2 | Solid forms of an azocyclic amide | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-06-23 | — | — | US | disclosed |
| US-20140127322-A1 | SOLID FORMS OF AN AZOCYCLIC AMIDE | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-05-08 | — | — | US | disclosed |
| US-8669277-B2 | Solid forms of an azocyclic amide | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-03-11 | — | — | US | disclosed |
| US-20120034315-A1 | SOLID FORMS OF AN AZOCYCLIC AMIDE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140127322-A1 | SOLID FORMS OF AN AZOCYCLIC AMIDE | NOD1, NUAK1, DDT | POLB 3860/4885RIPK1 682/4885MAPT 3032/4885 |
| US-20120034315-A1 | SOLID FORMS OF AN AZOCYCLIC AMIDE | NOD1, NUAK1, DDT | POLB 3860/4885RIPK1 682/4885MAPT 3032/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.