Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19525864 | 1.00 | POLB (0.35) | POLBNPC1RAB9APTPN1MEN1 | |
| SCHEMBL10163553 | 0.86 | POLB (0.35) | POLBNPC1RAB9AMEN1KMT2A | |
| SCHEMBL564213 | 0.86 | POLB (0.35) | POLBNPC1RAB9AMEN1KMT2A | |
| SCHEMBL19525865 | 0.81 | POLB (0.38) | POLBNPC1RAB9AMEN1KMT2A | |
| SCHEMBL193085 | 0.81 | POLB (0.38) | POLBNPC1RAB9AMEN1KMT2A | |
| SCHEMBL3689235 | 0.78 | TSHR (0.47) | PTPN1GSK3B | |
| SCHEMBL3680890 | 0.78 | TSHR (0.47) | PTPN1GSK3B | |
| SCHEMBL192351 | 0.78 | POLB (0.37) | POLBNPC1RAB9AMEN1KMT2A | |
| SCHEMBL19525866 | 0.78 | POLB (0.37) | POLBNPC1RAB9AMEN1KMT2A | |
| SCHEMBL28632237 | 0.74 | LMNA (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8669277-B2 | Solid forms of an azocyclic amide | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-03-11 | — | — | US | claimed |
| EP-2421861-B1 | SOLID FORMS OF AN AZOCYCLIC AMIDE | DU PONT (US) | 2013-01-16 | — | — | EP | claimed |
| EP-2421861-A1 | SOLID FORMS OF AN AZOCYCLIC AMIDE | E. I. du Pont de Nemours and Company (US) | 2012-02-29 | — | — | EP | claimed |
| US-20120034315-A1 | SOLID FORMS OF AN AZOCYCLIC AMIDE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-02-09 | — | — | US | claimed |
| WO-2010123791-A1 | SOLID FORMS OF AN AZOCYCLIC AMIDE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-10-28 | — | — | WO | claimed |
| CN-114685481-A | Preparation method of oxathiapiprolin | 南通泰禾化工股份有限公司 | 2022-07-01 | — | — | CN | disclosed |
| EP-3265446-B1 | PROCESS FOR PREPARING SUBSTITUTED PHENYLISOXAZOLINE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2019-08-14 | — | — | EP | disclosed |
| US-20180030002-A1 | Process for preparing substituted phenylisoxazoline derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-02-01 | — | — | US | disclosed |
| US-9090604-B2 | Fungicidal azocyclic amides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-07-28 | — | — | US | disclosed |
| US-9090604-B2 | Fungicidal azocyclic amides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-07-28 | — | — | US | disclosed |
| US-9062040-B2 | Solid forms of an azocyclic amide | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-06-23 | — | — | US | disclosed |
| EP-2521450-B1 | FUNGICIDAL HETEROCYCLIC COMPOUNDS | DU PONT (US) | 2015-02-25 | — | — | EP | disclosed |
| US-20110224258-A1 | FUNGICIDAL HETEROCYCLIC COMPOUNDS | E.I. DU PONT DE NEMOURS AND COMPANY (DE) | 2011-09-15 | — | — | US | disclosed |
| EP-2358709-A2 | FUNGICIDAL HETEROCYCLIC COMPOUNDS | E. I. du Pont de Nemours and Company (US) | 2011-08-24 | — | — | EP | disclosed |
| WO-2011085170-A1 | FUNGICIDAL HETEROCYCLIC COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-07-14 | — | — | WO | disclosed |
| EP-2260032-A2 | FUNGICIDAL HETERCYCLIC COMPOUNDS | E. I. du Pont de Nemours and Company (US) | 2010-12-15 | — | — | EP | disclosed |
| US-20100292275-A1 | FUNGICIDAL HETEROCYCLIC COMPOUNDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-11-18 | — | — | US | disclosed |
| WO-2010123791-A1 | SOLID FORMS OF AN AZOCYCLIC AMIDE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-10-28 | — | — | WO | disclosed |
| WO-2010065579-A2 | FUNGICIDAL HETEROCYCLIC COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-06-10 | — | — | WO | disclosed |
| WO-2009094445-A2 | FUNGICIDAL HETERCYCLIC COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-07-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224258-A1 | FUNGICIDAL HETEROCYCLIC COMPOUNDS | NOX1, XDH, CBR1 | POLB 4340/4885NPC1 961/4885RAB9A 664/4885 |
| US-20100292275-A1 | FUNGICIDAL HETEROCYCLIC COMPOUNDS | CYP1B1, CBR1, NOX1 | POLB 4093/4885NPC1 262/4885RAB9A 863/4885 |
| US-20180030002-A1 | Process for preparing substituted phenylisoxazoline derivatives | CYP3A7, CYP3A4, CYP4X1 | POLB 1028/4885NPC1 2178/4885RAB9A 3725/4885 |
| US-20120034315-A1 | SOLID FORMS OF AN AZOCYCLIC AMIDE | NOD1, NUAK1, DDT | POLB 3860/4885NPC1 285/4885RAB9A 2573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.