Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | PRKDC | P78527 | 1/20 | 0.46 |
| ▸ | CTSH | P09668 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | GALR2 | O43603 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | VCP | P55072 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28978906 | 0.84 | CTSB (0.68) | CTSBALDH1A1TDP1MAPTKDM4E | |
| SCHEMBL2087414 | 0.77 | ALDH1A1 (0.58) | ALDH1A1TDP1MAPTKDM4ECYP3A4 | |
| SCHEMBL11058082 | 0.76 | CTSB (0.68) | CTSBALDH1A1TDP1MAPTKDM4E | |
| Methoxymethane SCHEMBL7777573 | 0.76 | CTSB (0.86) | CTSBALDH1A1TDP1MAPTKDM4E | |
| SCHEMBL28577614 | 0.75 | ALDH1A1 (0.50) | CTSBALDH1A1TDP1MAPTKDM4E | |
| SCHEMBL31032881 | 0.75 | CTSB (0.61) | CTSBALDH1A1TDP1MAPTKDM4E | |
| SCHEMBL224904 | 0.74 | ALDH1A1 (0.56) | ALDH1A1TDP1MAPTKDM4ECYP3A4 | |
| SCHEMBL29800558 | 0.73 | ALDH1A1 (0.68) | ALDH1A1TDP1MAPTKDM4ECYP3A4 | |
| SCHEMBL210330 | 0.73 | ALDH1A1 (0.68) | ALDH1A1TDP1MAPTKDM4ECYP3A4 | |
| SCHEMBL426021 | 0.73 | ALDH1A1 (0.56) | ALDH1A1TDP1MAPTKDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8741917-B2 | Benzo [C] phenanthridines as antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2014-06-03 | — | — | US | disclosed |
| US-20120022061-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | RUGTERS, THE STATE UNIVERSITY OF NEW JERSEY | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022061-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | CCNT1, XPO4, XDH | CTSB 1625/4885ALDH1A1 3095/4885TDP1 1005/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.