SCHEMBL10165322

SCHEMBL10165322

C=Cc1ccc(N(c2ccccc2)c2cccs2)cc1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.42
TSHR P16473 1/20 0.42
MAPT P10636 2/20 0.33
KDM4E B2RXH2 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
MAPK1 P28482 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
RELA Q04206 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10165321 0.91 ALDH1A1 (0.41) ALDH1A1TSHR
SCHEMBL2681787 0.84 ALDH1A1 (0.39) ALDH1A1TSHRMAPTKDM4ECYP1A2
SCHEMBL12114947 0.80 ALDH1A1 (0.59) ALDH1A1TSHRMAPTKDM4ECYP1A2
SCHEMBL172194 0.80 ALDH1A1 (0.59) ALDH1A1TSHRMAPTKDM4ECYP1A2
SCHEMBL99027 0.80 ALDH1A1 (0.59) ALDH1A1TSHRMAPTKDM4ECYP1A2
SCHEMBL1177035 0.80 ALDH1A1 (0.59) ALDH1A1TSHRMAPTKDM4ECYP1A2
SCHEMBL20386511 0.80 ALDH1A1 (0.39) ALDH1A1TSHRMAPTKDM4ECYP1A2
SCHEMBL9551640 0.78 ALDH1A1 (0.35) ALDH1A1MAPTKDM4ECYP1A2CYP3A4
SCHEMBL10165323 0.78 DPP4 (0.37) ALDH1A1TSHRMAPTKDM4EL3MBTL1
SCHEMBL17012389 0.75 NOTUM (0.37) ALDH1A1TSHRMAPTKDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8338691-B2 Photoelectric conversion element and imaging device FUJIFILM CORPORATION (JP) 2012-12-25 US disclosed
US-8258506-B2 Photoelectric conversion device, production method thereof and imaging device FUJIFILM CORPORATION (JP) 2012-09-04 US disclosed
US-20120080585-A1 PHOTOELECTRIC CONVERSION ELEMENT, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVING METHOD FUJIFILM CORPORATION (JP) 2012-04-05 US disclosed
US-20100308311-A1 PHOTOELECTRIC CONVERSION DEVICE AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2010-12-09 US disclosed
US-20100308312-A1 PHOTOELECTRIC CONVERSION DEVICE, PRODUCTION METHOD THEREOF AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2010-12-09 US disclosed
US-20090223566-A1 PHOTOELECTRIC CONVERSION ELEMENT AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2009-09-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120080585-A1 PHOTOELECTRIC CONVERSION ELEMENT, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVING METHOD SUN2, CYBA, PPOX ALDH1A1 1609/4885TSHR 3845/4885MAPT 342/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.