SCHEMBL10165323

SCHEMBL10165323

C=Cc1ccc(N(c2cccs2)c2ccc(-c3cccs3)s2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 4/20 0.37
LTA4H P09960 1/20 0.35
ALDH1A1 P00352 4/20 0.35
KDM4E B2RXH2 3/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
GAA P10253 3/20 0.33
L3MBTL1 Q9Y468 3/20 0.33
LMNA P02545 2/20 0.33
GLA P06280 2/20 0.33
MAPT P10636 2/20 0.33
MEN1 O00255 2/20 0.33
POLB P06746 2/20 0.33
HPGD P15428 2/20 0.33
CASP1 P29466 2/20 0.33
CASP7 P55210 2/20 0.33
KMT2A Q03164 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
HSD17B10 Q99714 2/20 0.33
HDAC1 Q13547 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12084933 0.96 DPP4 (0.40) DPP4LTA4HALDH1A1KDM4ENPC1
SCHEMBL10165321 0.85 ALDH1A1 (0.41) ALDH1A1TSHR
SCHEMBL10134163 0.78 ALDH1A1 (0.42) DPP4ALDH1A1NPC1RAB9AGAA
SCHEMBL10165322 0.78 ALDH1A1 (0.42) ALDH1A1KDM4EL3MBTL1LMNAMAPT
SCHEMBL10134180 0.75 MAOB (0.36) DPP4ALDH1A1KDM4ENPC1RAB9A
SCHEMBL10134193 0.74 TNFRSF1A (0.42) DPP4ALDH1A1KDM4ENPC1RAB9A
SCHEMBL10134162 0.74 ALDH1A1 (0.45) DPP4ALDH1A1NPC1RAB9AMAPT
SCHEMBL15259638 0.73 DPP4 (0.49) DPP4LTA4HALDH1A1KDM4ENPC1
SCHEMBL10134172 0.70 MAOB (0.38) DPP4ALDH1A1KDM4ENPC1RAB9A
SCHEMBL8994875 0.70 APP (0.46) DPP4LTA4HALDH1A1KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8338691-B2 Photoelectric conversion element and imaging device FUJIFILM CORPORATION (JP) 2012-12-25 US disclosed
US-20120080585-A1 PHOTOELECTRIC CONVERSION ELEMENT, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVING METHOD FUJIFILM CORPORATION (JP) 2012-04-05 US disclosed
US-20110063485-A1 PHOTOELECTRIC CONVERSION DEVICE, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVE METHODS FUJIFILM CORPORATION (JP) 2011-03-17 US disclosed
US-20100308311-A1 PHOTOELECTRIC CONVERSION DEVICE AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2010-12-09 US disclosed
US-20090223566-A1 PHOTOELECTRIC CONVERSION ELEMENT AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2009-09-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120080585-A1 PHOTOELECTRIC CONVERSION ELEMENT, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVING METHOD SUN2, CYBA, PPOX DPP4 3314/4885LTA4H 2823/4885ALDH1A1 1609/4885
US-20110063485-A1 PHOTOELECTRIC CONVERSION DEVICE, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVE METHODS PPOX, CRY1, FTO DPP4 3156/4885LTA4H 2582/4885ALDH1A1 1665/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.