Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 4/20 | 0.61 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.61 |
| ▸ | MMP3 | P08254 | 1/20 | 0.61 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.41 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 4/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 4/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8246189 | 0.91 | MMP13 (0.65) | MMP13ADAMTS4MMP3RAF1P2RX7 | |
| SCHEMBL10162390 | 0.88 | MMP13 (0.56) | MMP13ADAMTS4MMP3RAF1P2RX7 | |
| SCHEMBL10165476 | 0.86 | MMP13 (0.48) | MMP13ADAMTS4MMP3 | |
| SCHEMBL10165660 | 0.86 | SMN1; SMN2 (0.46) | MMP13ADAMTS4MMP3 | |
| SCHEMBL10162288 | 0.84 | MMP13 (0.56) | MMP13ADAMTS4MMP3RAF1P2RX7 | |
| SCHEMBL8221216 | 0.83 | MMP13 (0.54) | MMP13ADAMTS4MMP3RAF1P2RX7 | |
| SCHEMBL10165948 | 0.81 | MMP13 (0.57) | MMP13ADAMTS4MMP3RAF1P2RX7 | |
| SCHEMBL10166973 | 0.81 | MMP13 (0.57) | MMP13ADAMTS4MMP3RAF1P2RX7 | |
| SCHEMBL8228320 | 0.81 | MMP13 (0.53) | MMP13ADAMTS4MMP3RAF1P2RX7 | |
| SCHEMBL10162295 | 0.81 | MMP13 (0.55) | MMP13ADAMTS4MMP3RAF1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120015920-A1 | HETEROBICYCLIC METALLOPROTEASE INHIBITORS | ALANTOS PHARMACEUTICALS HOLDING, INC. (US) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015920-A1 | HETEROBICYCLIC METALLOPROTEASE INHIBITORS | MMP13, TIMP3, MMP3 | MMP13 1/4885ADAMTS4 38/4885MMP3 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.