Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | CCR3 | P51677 | 1/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7952371 | 0.81 | ACHE (0.66) | ACHECCR3ABL1RIN1SIGMAR1 | |
| SCHEMBL7852368 | 0.80 | ACHE (0.64) | ACHECCR3ABL1RIN1SIGMAR1 | |
| SCHEMBL20012633 | 0.78 | ACHE (0.62) | ACHECCR3ABL1RIN1SIGMAR1 | |
| SCHEMBL19770184 | 0.78 | ACHE (0.62) | ACHECCR3ABL1RIN1SIGMAR1 | |
| SCHEMBL4636684 | 0.78 | ACHE (0.62) | ACHECCR3ABL1RIN1SIGMAR1 | |
| SCHEMBL19879957 | 0.78 | ACHE (0.67) | ACHECCR3ABL1RIN1SIGMAR1 | |
| SCHEMBL7651915 | 0.78 | ACHE (0.62) | ACHECCR3ABL1RIN1SIGMAR1 | |
| SCHEMBL6750641 | 0.77 | OPRM1 (0.54) | ACHEABL1RIN1SIGMAR1ALDH1A1 | |
| SCHEMBL13515107 | 0.76 | ACHE (0.64) | ACHECCR3ABL1RIN1SIGMAR1 | |
| SCHEMBL1727229 | 0.76 | BACE1 (0.65) | ACHECCR3SIGMAR1DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106062-B1 | Calcium channel blockers | DIAKRON PHARMACEUTICALS, INC. (US) | 2012-01-31 | — | — | US | disclosed |