SCHEMBL10166228

SCHEMBL10166228

CC(C)NCNC(=O)CCCN1C(=N)N(C)CC1=O

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ HPGD P15428 3/20 0.36
▸ SMN1; SMN2 Q16637 2/20 0.36
▸ HTT P42858 1/20 0.36
▸ ALDH1A1 P00352 5/20 0.33
▸ TP53 P04637 1/20 0.31
▸ POLB P06746 1/20 0.31
▸ LMNA P02545 1/20 0.31
▸ THRB P10828 1/20 0.31
▸ MAPT P10636 1/20 0.30
▸ RECQL P46063 1/20 0.30
▸ GAA P10253 1/20 0.30
▸ MEN1 O00255 1/20 0.30
▸ KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15672233 0.87 SMN1; SMN2 (0.39) HPGDSMN1; SMN2HTTALDH1A1TP53
SCHEMBL19675107 0.78 KDM4E (0.35) HPGDSMN1; SMN2HTTALDH1A1POLB
SCHEMBL3425614 0.77 MEN1 (0.32) ALDH1A1LMNAGAAMEN1KMT2A
SCHEMBL3428460 0.75 PTGS1 (0.41) HPGDSMN1; SMN2HTTALDH1A1LMNA
SCHEMBL3425627 0.75 PAOX (0.34) ALDH1A1MAPTRECQL
SCHEMBL5035064 0.75 HDAC6 (0.32) ALDH1A1MAPTRECQL
SCHEMBL19675040 0.74 HDAC6 (0.31) ALDH1A1MAPTRECQL
SCHEMBL20081691 0.72 KDM4E (0.35) MAPTRECQL
SCHEMBL19229985 0.71 PLA2G7 (0.31) —
SCHEMBL31188474 0.69 KDM4E (0.42) MAPTRECQLMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170233798-A1 NMR SYSTEMS AND METHODS FOR THE RAPID DETECTION OF ANALYTES T2 BIOSYSTEMS, INC. (US) 2017-08-17 — — US disclosed
US-9714940-B2 NMR systems and methods for the rapid detection of analytes T2 BIOSYSTEMS, INC. (US) 2017-07-25 — — US disclosed
US-9702852-B2 NMR systems and methods for the rapid detection of analytes T2 BIOSYSTEMS, INC. (US) 2017-07-11 — — US disclosed
US-9488648-B2 NMR systems and methods for the rapid detection of analytes T2 BIOSYSTEMS, INC. (US) 2016-11-08 — — US disclosed
US-9360457-B2 NMR systems and methods for the rapid detection of analytes T2 BIOSYSTEMS, INC. (US) 2016-06-07 — — US disclosed
US-9046493-B2 NMR systems and methods for the rapid detection of analytes T2 BIOSYSTEMS, INC. (US) 2015-06-02 — — US disclosed
US-8883423-B2 NMR systems and methods for the rapid detection of analytes T2 BIOSYSTEMS, INC. (US) 2014-11-11 — — US disclosed
US-20140120523-A1 NMR SYSTEMS AND METHODS FOR THE RAPID DETECTION OF ANALYTES T2 BIOSYSTEMS, INC. (US) 2014-05-01 — — US disclosed
US-20130273522-A1 NMR SYSTEMS AND METHODS FOR THE RAPID DETECTION OF ANALYTES T2 BIOSYSTEMS, INC. 2013-10-17 — — US disclosed
US-20130273523-A1 NMR SYSTEMS AND METHODS FOR THE RAPID DETECTION OF ANALYTES T2 BIOSYSTEMS, INC. 2013-10-17 — — US disclosed
US-20130266944-A1 NMR SYSTEMS AND METHODS FOR THE RAPID DETECTION OF ANALYTES T2 Biosystems. Inc. (US) 2013-10-10 — — US disclosed
US-20130260367-A1 NMR SYSTEMS AND METHODS FOR THE RAPID DETECTION OF ANALYTES T2 BIOSYSTEMS, INC. (US) 2013-10-03 — — US disclosed
US-20130244238-A1 NMR SYSTEMS AND METHODS FOR THE RAPID DETECTION OF ANALYTES T2 BIOSYSTEMS, INC. (US) 2013-09-19 — — US disclosed
US-20130095494-A1 NMR SYSTEMS AND METHODS FOR THE RAPID DETECTION OF ANALYTES T2 BIOSYSTEMS, INC. (US) 2013-04-18 — — US disclosed
US-8409807-B2 NMR systems and methods for the rapid detection of analytes T2 BIOSYSTEMS, INC. (US) 2013-04-02 — — US disclosed
US-20130029345-A1 NMR SYSTEMS AND METHODS FOR THE RAPID DETECTION OF ANALYTES T2 BIOSYSTEMS, INC. (US) 2013-01-31 — — US disclosed
US-20120301888-A1 NMR SYSTEMS AND METHODS FOR THE RAPID DETECTION OF ANALYTES T2 BIOSYSTEMS, INC. (US) 2012-11-29 — — US disclosed
US-20120164644-A1 NMR SYSTEMS AND METHODS FOR THE RAPID DETECTION OF ANALYTES T2 BIOSYSTEMS, INC. (US) 2012-06-28 — — US disclosed
Send feedback