Sugi Predict

Sugi Predict / Compounds / SCHEMBL10166468

SCHEMBL10166468

SCHEMBL10166468

Cc1nnsc1-c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDO2 P48775 1/20 0.59
▸ ALDH1A1 P00352 6/20 0.49
▸ HSD17B10 Q99714 2/20 0.49
▸ KDM4E B2RXH2 2/20 0.49
▸ HPGD P15428 1/20 0.49
▸ CYP1A2 P05177 1/20 0.42
▸ CYP2C9 P11712 1/20 0.42
▸ LMNA P02545 3/20 0.42
▸ ALOX5 P09917 1/20 0.41
▸ KMT2A Q03164 3/20 0.41
▸ GAA P10253 3/20 0.41
▸ MEN1 O00255 2/20 0.41
▸ NPC1 O15118 2/20 0.41
▸ RAB9A P51151 2/20 0.41
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ TP53 P04637 1/20 0.41
▸ MAPT P10636 1/20 0.41
▸ NFKB1 P19838 1/20 0.41
▸ NFKB2 Q00653 1/20 0.41
▸ RELA Q04206 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11768418 0.79 ALDH1A1 (0.44) TDO2ALDH1A1HSD17B10KDM4EHPGD
SCHEMBL8131400 0.79 ALDH1A1 (0.39) TDO2ALDH1A1HSD17B10KDM4EHPGD
SCHEMBL170710 0.76 TDO2 (0.61) TDO2ALDH1A1HSD17B10KDM4ECYP1A2
SCHEMBL9563862 0.74 TDO2 (0.59) TDO2ALDH1A1HSD17B10KDM4ECYP1A2
SCHEMBL544158 0.74 TDO2 (1.00) TDO2ALDH1A1HSD17B10KDM4ECYP1A2
SCHEMBL9168462 0.74 TDO2 (0.59) TDO2ALDH1A1HSD17B10KDM4ECYP1A2
SCHEMBL22684941 0.74 TDO2 (0.59) TDO2ALDH1A1HSD17B10KDM4ECYP1A2
SCHEMBL367037 0.74 TDO2 (0.59) TDO2ALDH1A1HSD17B10KDM4ECYP1A2
SCHEMBL14048210 0.74 TDO2 (0.53) TDO2ALDH1A1HSD17B10KDM4ECYP1A2
SCHEMBL20033945 0.74 TDO2 (0.53) TDO2ALDH1A1HSD17B10KDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11659766-B2 Organic semiconductor material for electron transport DAEGU GYEONGBUK INSTITUTE OF SCIENCE & TECHNOLOGY (KR) 2023-05-23 — — US disclosed
US-11659766-B2 Organic semiconductor material for electron transport DAEGU GYEONGBUK INSTITUTE OF SCIENCE & TECHNOLOGY (KR) 2023-05-23 — — US disclosed
US-20190189933-A1 ORGANIC SEMICONDUCTOR MATERIAL FOR ELECTRON TRANSPORT DAEGU GYEONGBUK INSTITUTE OF SCIENCE & TECHNOLOGY (KR) 2019-06-20 — — US disclosed
US-9941479-B2 Tetradentate cyclometalated platinum complexes containing 9,10-dihydroacridine and its analogues ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2018-04-10 — — US disclosed
US-8980837-B2 Inhibitors of IAP GENENTECH, INC. (US) 2015-03-17 — — US disclosed
US-8980837-B2 Inhibitors of IAP GENENTECH, INC. (US) 2015-03-17 — — US disclosed
US-8907092-B2 Inhibitors of IAP GENENTECH, INC. (US) 2014-12-09 — — US disclosed
US-8907092-B2 Inhibitors of IAP GENENTECH, INC. (US) 2014-12-09 — — US disclosed
US-20120202750-A1 INHIBITORS OF IAP GENENTECH, INC. (US) 2012-08-09 — — US disclosed
US-20120202750-A1 INHIBITORS OF IAP GENENTECH, INC. (US) 2012-08-09 — — US disclosed
US-8110568-B2 Inhibitors of IAP GENENTECH, INC. (US) 2012-02-07 — — US disclosed
US-20110230419-A1 IAP BINDING COMPOUNDS NUEVOLUTION A/S (DK) 2011-09-22 — — US disclosed
US-20110077265-A1 INHIBITORS OF IAP GENENTECH, INC. (US) 2011-03-31 — — US disclosed
US-20110077265-A1 INHIBITORS OF IAP GENENTECH, INC. (US) 2011-03-31 — — US disclosed
US-20110046066-A1 INHIBITORS OF IAP GENENTECH, INC. (US) 2011-02-24 — — US disclosed
US-20110046066-A1 INHIBITORS OF IAP GENENTECH, INC. (US) 2011-02-24 — — US disclosed
US-20100256115-A1 INHIBITORS OF IAP COHEN FREDERICK 2010-10-07 — — US disclosed
US-20100256115-A1 INHIBITORS OF IAP COHEN FREDERICK 2010-10-07 — — US disclosed
US-20070299052-A1 Inhibitors of IAP GENENTECH, INC. (US) 2007-12-27 — — US disclosed
US-7244851-B2 1-[2-Cyclohexyl-2-(2-methylamino-propionylamino)-acetyl]-pyrrolidine-2-carboxylic acid (2-phenyl-2H-pyrazol-3-yl)-amide; inhibitors of IAP, for treating malignancies GENENTECH, INC. (US) 2007-07-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110230419-A1 IAP BINDING COMPOUNDS BIRC5, BIRC7, BIRC3 TDO2 4619/4885ALDH1A1 2947/4885HSD17B10 3957/4885
US-20070299052-A1 Inhibitors of IAP XIAP, BIRC5, BIRC3 TDO2 4611/4885ALDH1A1 4132/4885HSD17B10 4717/4885
US-20110046066-A1 INHIBITORS OF IAP BIRC5, XIAP, BIRC3 TDO2 4711/4885ALDH1A1 4236/4885HSD17B10 4749/4885
US-20120202750-A1 INHIBITORS OF IAP XIAP, BIRC5, BIRC3 TDO2 4611/4885ALDH1A1 4132/4885HSD17B10 4717/4885
US-20100256115-A1 INHIBITORS OF IAP XIAP, BIRC5, BIRC3 TDO2 4611/4885ALDH1A1 4132/4885HSD17B10 4717/4885
US-20110077265-A1 INHIBITORS OF IAP XIAP, BIRC5, BIRC2 TDO2 4768/4885ALDH1A1 4304/4885HSD17B10 4416/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.