Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 10/20 | 0.57 |
| ▸ | DRD2 | P14416 | 3/20 | 0.57 |
| ▸ | DRD1 | P21728 | 3/20 | 0.57 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 2/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | NOS1 | P29475 | 2/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | DRD5 | P21918 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL659100 | 0.88 | TAAR1 (0.70) | TAAR1DRD2DRD1HTR2ACYP2A6 | |
| Hydrochloric Acid SCHEMBL3957562 | 0.85 | TAAR1 (0.67) | TAAR1DRD2DRD1HTR2ACYP2A6 | |
| SCHEMBL9313214 | 0.85 | MEN1 (0.46) | TAAR1DRD2DRD1NOS1CYP2D6 | |
| SCHEMBL646951 | 0.83 | ALDH1A1 (0.43) | TAAR1LOXL2NOS1CYP2D6NOS3 | |
| SCHEMBL2642524 | 0.81 | TAAR1 (0.61) | TAAR1DRD2DRD1HTR2ACYP2A6 | |
| SCHEMBL16624583 | 0.81 | LOXL2 (0.55) | TAAR1SMN1; SMN2LOXL2NOS1NOS3 | |
| SCHEMBL13313981 | 0.77 | CNR1 (0.42) | TAAR1DRD2DRD1DRD4DRD5 | |
| SCHEMBL171704 | 0.77 | TAAR1 (0.57) | TAAR1DRD2DRD1HTR2ACYP2A6 | |
| SCHEMBL207005 | 0.77 | TAAR1 (0.63) | TAAR1DRD2DRD1HTR2ACYP2A6 | |
| SCHEMBL3057497 | 0.77 | TAAR1 (0.63) | TAAR1DRD2DRD1HTR2ACYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088941-B2 | Glycogen synthase kinase-3 inhibitors | TEL AVIV UNIVERSITY FUTURE TECHNOLOGY DEVELOPMENT L.P. (IL) | 2012-01-03 | — | — | US | disclosed |