Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 9/20 | 0.50 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1017236 | 0.91 | DDR1 (0.52) | DDR1 | |
| SCHEMBL1018589 | 0.90 | DDR1 (0.48) | DDR1ADRA1D | |
| Hydrochloric Acid SCHEMBL1018259 | 0.89 | DDR1 (0.47) | DDR1ADRA1D | |
| SCHEMBL1017517 | 0.88 | DDR1 (0.39) | DDR1ADRA1DKDM4EALDH1A1RCE1 | |
| Hydrochloric Acid SCHEMBL1020060 | 0.88 | DDR1 (0.39) | DDR1ADRA1DKDM4EALDH1A1RCE1 | |
| Hydrochloric Acid SCHEMBL1018237 | 0.85 | ALDH1A1 (0.45) | ADRA1DKDM4EALDH1A1RCE1 | |
| Hydrochloric Acid SCHEMBL1017169 | 0.85 | ALDH1A1 (0.46) | ROCK2ROCK1KDM4EALDH1A1RCE1 | |
| Hydrochloric Acid SCHEMBL1017474 | 0.84 | USP2 (0.46) | DDR1ROCK2ROCK1ALDH1A1 | |
| SCHEMBL15703882 | 0.84 | EPHX2 (0.46) | DDR1ADRA1DROCK2ROCK1KDM4E | |
| Hydrochloric Acid SCHEMBL1017391 | 0.84 | EPHX2 (0.40) | DDR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2271624-A1 | IMINOPYRIDINE DERIVATIVES AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2011-01-12 | — | — | EP | disclosed |
| WO-2009131245-A1 | IMINOPYRIDINE DERIVATIVES AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-29 | — | — | WO | disclosed |