SCHEMBL1017236

SCHEMBL1017236

CCS(=O)(=O)c1ccc(F)cc1CNC(=O)c1cc(Cl)c[nH]c1=N

nearest known ligand 0.52

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DDR1 Q08345 20/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1016771 0.91 DDR1 (0.50) DDR1
Hydrochloric Acid SCHEMBL1017474 0.85 USP2 (0.46) DDR1
Hydrochloric Acid SCHEMBL1017391 0.83 EPHX2 (0.40) DDR1
Hydrochloric Acid SCHEMBL1016430 0.82 KMT2A (0.43)
Hydrochloric Acid SCHEMBL1017169 0.82 ALDH1A1 (0.46)
SCHEMBL1018589 0.81 DDR1 (0.48) DDR1
Hydrochloric Acid SCHEMBL1018184 0.81 LMNA (0.48)
Hydrochloric Acid SCHEMBL1018259 0.80 DDR1 (0.47) DDR1
SCHEMBL1017517 0.79 DDR1 (0.39) DDR1
Hydrochloric Acid SCHEMBL1020060 0.78 DDR1 (0.39) DDR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2271624-A1 IMINOPYRIDINE DERIVATIVES AND USE THEREOF Takeda Pharmaceutical Company Limited (JP) 2011-01-12 EP disclosed
WO-2009131245-A1 IMINOPYRIDINE DERIVATIVES AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-10-29 WO disclosed