Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 9/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1020060 | 0.99 | DDR1 (0.39) | DDR1ADRA1DALDH1A1KDM4ERCE1 | |
| SCHEMBL1018589 | 0.91 | DDR1 (0.48) | DDR1ADRA1D | |
| Hydrochloric Acid SCHEMBL1018259 | 0.90 | DDR1 (0.47) | DDR1ADRA1D | |
| SCHEMBL1016771 | 0.88 | DDR1 (0.50) | DDR1ADRA1DALDH1A1KDM4ERCE1 | |
| Hydrochloric Acid SCHEMBL1018237 | 0.86 | ALDH1A1 (0.45) | ADRA1DALDH1A1KDM4ERCE1MAPT | |
| SCHEMBL15703882 | 0.85 | EPHX2 (0.46) | DDR1ADRA1DALDH1A1KDM4ERCE1 | |
| Hydrochloric Acid SCHEMBL1017774 | 0.83 | DDR1 (0.48) | DDR1 | |
| Hydrochloric Acid SCHEMBL1017784 | 0.79 | DDR1 (0.45) | DDR1 | |
| SCHEMBL1017236 | 0.79 | DDR1 (0.52) | DDR1 | |
| SCHEMBL1019865 | 0.78 | CA1 (0.50) | ALDH1A1HSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2271624-A1 | IMINOPYRIDINE DERIVATIVES AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2011-01-12 | — | — | EP | disclosed |
| WO-2009131245-A1 | IMINOPYRIDINE DERIVATIVES AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-29 | — | — | WO | disclosed |