Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 6/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NCK1 | P16333 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30206597 | 0.81 | KDM4E (0.48) | CYP1A2CYP2A6TDP1KDM4ESMN1; SMN2 | |
| SCHEMBL10168165 | 0.79 | CYP2A6 (0.40) | CYP2A6TDP1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL10168166 | 0.79 | CYP1A2 (0.40) | CYP1A2CYP2A6KDM4ESMN1; SMN2LMNA | |
| SCHEMBL9724136 | 0.77 | CYP2A6 (0.48) | CYP1A2CYP2A6TDP1KDM4ESMN1; SMN2 | |
| SCHEMBL30968718 | 0.76 | SYNJ2 (0.46) | SMN1; SMN2LMNAKMT2AMEN1MAPT | |
| SCHEMBL13144480 | 0.76 | ACHE (0.54) | CYP1A2CYP2A6TDP1KDM4ELMNA | |
| SCHEMBL21412991 | 0.76 | SYNJ2 (0.46) | SMN1; SMN2LMNAKMT2AMEN1MAPT | |
| SCHEMBL17187221 | 0.75 | CYP2A6 (0.50) | CYP1A2CYP2A6TDP1KDM4ESMN1; SMN2 | |
| SCHEMBL7936307 | 0.74 | KDM4E (0.46) | CYP1A2CYP2A6TDP1KDM4ESMN1; SMN2 | |
| SCHEMBL30929898 | 0.73 | ACHE (0.47) | CYP2A6TDP1KDM4ESMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1330456-B9 | N8,N13 -DISUBSTITUTED QUINO[4,3,2-KL]ACRIDINIUM SALTS AS THERAPEUTIC AGENTS | CANCER REC TECH LTD (GB) | 2012-01-25 | — | — | EP | disclosed |
| EP-1330456-B1 | N8,N13 -DISUBSTITUTED QUINO[4,3,2-KL]ACRIDINIUM SALTS AS THERAPEUTIC AGENTS | CANCER REC TECH LTD (GB) | 2011-06-15 | — | — | EP | disclosed |