Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HBB | P68871 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL383733 | 0.84 | TERT (0.43) | CYP1A2CYP2A6ACHEKDM4ELMNA | |
| SCHEMBL10167906 | 0.79 | CYP1A2 (0.50) | CYP1A2CYP2A6KDM4EMEN1USP2 | |
| SCHEMBL26437742 | 0.78 | CYP1A2 (0.39) | CYP1A2CYP2A6ACHEKDM4EMEN1 | |
| SCHEMBL9736974 | 0.78 | CYP1A2 (0.39) | CYP1A2CYP2A6ACHEKDM4EMAPT | |
| SCHEMBL21412991 | 0.73 | SYNJ2 (0.46) | ACHEMEN1LMNAMAPTHTT | |
| SCHEMBL30968718 | 0.73 | SYNJ2 (0.46) | ACHEMEN1LMNAMAPTHTT | |
| SCHEMBL13144480 | 0.73 | ACHE (0.54) | CYP1A2CYP2A6ACHEKDM4EMEN1 | |
| SCHEMBL26431685 | 0.71 | CYP19A1 (0.31) | — | |
| SCHEMBL30929898 | 0.70 | ACHE (0.47) | CYP2A6ACHEKDM4EMEN1LMNA | |
| SCHEMBL1044982 | 0.70 | ACHE (0.47) | CYP2A6ACHEKDM4EMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1330456-B9 | N8,N13 -DISUBSTITUTED QUINO[4,3,2-KL]ACRIDINIUM SALTS AS THERAPEUTIC AGENTS | CANCER REC TECH LTD (GB) | 2012-01-25 | — | — | EP | disclosed |
| EP-1330456-B1 | N8,N13 -DISUBSTITUTED QUINO[4,3,2-KL]ACRIDINIUM SALTS AS THERAPEUTIC AGENTS | CANCER REC TECH LTD (GB) | 2011-06-15 | — | — | EP | disclosed |