Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | GPR3 | P46089 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14802158 | 0.81 | MAPT (0.68) | HTTMAPTGPR3KDM1AATM | |
| SCHEMBL10977307 | 0.79 | HTT (0.66) | HTTMAPTGPR3KDM1AATM | |
| SCHEMBL382974 | 0.79 | HTT (0.66) | HTTMAPTGPR3KDM1AATM | |
| SCHEMBL9352178 | 0.79 | HTT (1.00) | HTTMAPTGPR3KDM1AATM | |
| SCHEMBL21312375 | 0.79 | GPR3 (0.71) | HTTMAPTGPR3KDM1AATM | |
| SCHEMBL29466066 | 0.79 | GPR3 (0.71) | HTTMAPTGPR3ATMCYP2C19 | |
| SCHEMBL53107 | 0.79 | GPR3 (0.71) | HTTMAPTGPR3ATMCYP2C19 | |
| SCHEMBL13633669 | 0.76 | HTT (0.61) | HTTMAPTGPR3KDM1AATM | |
| SCHEMBL21564036 | 0.76 | HTT (0.61) | HTTMAPTGPR3KDM1AATM | |
| SCHEMBL10168172 | 0.74 | MAPT (0.59) | HTTMAPTGPR3KDM1AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1330456-B9 | N8,N13 -DISUBSTITUTED QUINO[4,3,2-KL]ACRIDINIUM SALTS AS THERAPEUTIC AGENTS | CANCER REC TECH LTD (GB) | 2012-01-25 | — | — | EP | disclosed |
| EP-1330456-B1 | N8,N13 -DISUBSTITUTED QUINO[4,3,2-KL]ACRIDINIUM SALTS AS THERAPEUTIC AGENTS | CANCER REC TECH LTD (GB) | 2011-06-15 | — | — | EP | disclosed |