SCHEMBL382974

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18566674	0.85	GPR3 (0.58)	HTTMAPTGPR3HSD17B10KDM4E
	SCHEMBL383526	0.82	NTRK1 (0.48)	HTTMAPTATMKDM1ANTRK1
	SCHEMBL14802158	0.81	MAPT (0.68)	HTTMAPTGPR3ATMCYP2C19
	SCHEMBL10977307	0.79	HTT (0.66)	HTTMAPTGPR3ATMCYP2C19
	SCHEMBL10167907	0.79	HTT (0.66)	HTTMAPTGPR3ATMCYP2C19
	SCHEMBL9352178	0.79	HTT (1.00)	HTTMAPTGPR3ATMCYP2C19
	SCHEMBL29466066	0.79	GPR3 (0.71)	HTTMAPTGPR3ATMCYP2C19
	SCHEMBL21312375	0.79	GPR3 (0.71)	HTTMAPTGPR3ATMCYP2C19
	SCHEMBL21975440	0.79	GPR3 (0.44)	HTTMAPTGPR3ALDH1A1NQO2
	SCHEMBL53107	0.79	GPR3 (0.71)	HTTMAPTGPR3ATMCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.