Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 4/20 | 0.42 |
| ▸ | CA9 | Q16790 | 8/20 | 0.42 |
| ▸ | CA1 | P00915 | 7/20 | 0.42 |
| ▸ | CA2 | P00918 | 7/20 | 0.42 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.40 |
| ▸ | IDH2 | P48735 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | FCGR3B | O75015 | 1/20 | 0.38 |
| ▸ | FCGR1A | P12314 | 1/20 | 0.38 |
| ▸ | FCGR2A | P12318 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9924663 | 0.94 | PDE5A (0.49) | PDE5AKCNH3SNCAKDM4ELMNA | |
| SCHEMBL13705645 | 0.93 | CA1 (0.46) | CA9CA1CA2KCNH3CA12 | |
| SCHEMBL15840096 | 0.92 | KCNH3 (0.42) | PDE5ACA9CA1CA2KCNH3 | |
| SCHEMBL10169002 | 0.91 | KMT2A (0.46) | PDE5AKCNH3IDH2KDM4ELMNA | |
| SCHEMBL10168986 | 0.89 | CA9 (0.50) | CA9CA1CA2KCNH3CA12 | |
| SCHEMBL15804169 | 0.88 | GBA1 (0.39) | PDE5ACA9CA1CA2KCNH3 | |
| SCHEMBL15804187 | 0.88 | RECQL (0.50) | CA9CA1CA2KCNH3IDH2 | |
| SCHEMBL10198856 | 0.88 | ROCK1 (0.41) | PDE5ACA9CA1CA2KCNH3 | |
| SCHEMBL12421840 | 0.87 | CA9 (0.47) | CA9CA1CA2CA12MAPT | |
| SCHEMBL13012818 | 0.87 | GBA1 (0.41) | PDE5ACA9CA1CA2KCNH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8657433-B2 | Porphyrazine coloring matter, ink composition, recording method, and colored object | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2014-02-25 | — | — | US | disclosed |
| US-20120081457-A1 | PORPHYRAZINE COLORING MATTER, INK COMPOSITION, RECORDING METHOD, AND COLORED OBJECT | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2012-04-05 | — | — | US | disclosed |