Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | VCP | P55072 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 4/20 | 0.41 |
| ▸ | RHOA | P61586 | 1/20 | 0.41 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.39 |
| ▸ | IDH2 | P48735 | 1/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9924663 | 0.91 | PDE5A (0.49) | PDE5AKCNH3KDM4ELMNAMAPT | |
| SCHEMBL10168992 | 0.91 | PDE5A (0.42) | PDE5AKCNH3IDH2KDM4ELMNA | |
| SCHEMBL15840096 | 0.88 | KCNH3 (0.42) | PDE5AKCNH3IDH2 | |
| SCHEMBL10168999 | 0.87 | VCP (0.47) | VCPPDE5ARHOASYKKCNH3 | |
| SCHEMBL13705645 | 0.84 | CA1 (0.46) | KCNH3 | |
| SCHEMBL15804187 | 0.84 | RECQL (0.50) | KCNH3IDH2MAPT | |
| SCHEMBL10198856 | 0.84 | ROCK1 (0.41) | PDE5AKCNH3IDH2NPC1RAB9A | |
| SCHEMBL15804169 | 0.84 | GBA1 (0.39) | PDE5AKCNH3IDH2 | |
| SCHEMBL13012818 | 0.83 | GBA1 (0.41) | PDE5AKCNH3IDH2 | |
| SCHEMBL12421840 | 0.83 | CA9 (0.47) | KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8657433-B2 | Porphyrazine coloring matter, ink composition, recording method, and colored object | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2014-02-25 | — | — | US | disclosed |
| US-20120081457-A1 | PORPHYRAZINE COLORING MATTER, INK COMPOSITION, RECORDING METHOD, AND COLORED OBJECT | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2012-04-05 | — | — | US | disclosed |