SCHEMBL9924663

SCHEMBL9924663

CS(=O)(=O)NCCNc1nc(NCc2ccccc2)nc(Nc2cccc(S(=O)(=O)O)c2)n1

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PDE5A O76074 4/20 0.49
KCNH3 Q9ULD8 6/20 0.48
LMNA P02545 3/20 0.44
MAPT P10636 3/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
KDM4E B2RXH2 2/20 0.44
MAPK1 P28482 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
HTT P42858 1/20 0.42
GPR55 Q9Y2T6 1/20 0.42
POLB P06746 1/20 0.42
SLC2A1 P11166 1/20 0.42
RECQL P46063 1/20 0.41
MCL1 Q07820 1/20 0.41
PTK2 Q05397 1/20 0.41
SNCA P37840 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10168992 0.94 PDE5A (0.42) PDE5AKCNH3LMNAMAPTSMN1; SMN2
SCHEMBL15840096 0.92 KCNH3 (0.42) PDE5AKCNH3RECQLMCL1PTK2
SCHEMBL10169002 0.91 KMT2A (0.46) PDE5AKCNH3LMNAMAPTSMN1; SMN2
SCHEMBL10169004 0.88 KCNH3 (0.51) PDE5AKCNH3RECQLMCL1
SCHEMBL15804169 0.88 GBA1 (0.39) PDE5AKCNH3RECQLMCL1PTK2
SCHEMBL13705645 0.88 CA1 (0.46) KCNH3RECQLMCL1SNCA
SCHEMBL10198856 0.88 ROCK1 (0.41) PDE5AKCNH3RECQLMCL1
SCHEMBL15804187 0.88 RECQL (0.50) KCNH3MAPTRECQLMCL1
SCHEMBL13012818 0.87 GBA1 (0.41) PDE5AKCNH3RECQLMCL1
SCHEMBL12421840 0.87 CA9 (0.47) MAPTPOLBPTK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9676951-B2 Ink-jet ink set SEIKO EPSON CORPORATION (JP) 2017-06-13 US disclosed
US-20140345494-A1 INK-JET INK SET SEIKO EPSON CORPORATION (JP) 2014-11-27 US disclosed
US-8876273-B2 Ink composition, ink jet recording method using the same and recorded material SEIKO EPSON CORPORATION (JP) 2014-11-04 US disclosed
US-8857965-B2 Ink compostion, recording method using the same and recorded material SEIKO EPSON CORPORATION (JP) 2014-10-14 US disclosed
US-8657433-B2 Porphyrazine coloring matter, ink composition, recording method, and colored object NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2014-02-25 US disclosed
US-20120148807-A1 INK COMPOSITION, INK JET RECORDING METHOD USING THE SAME AND RECORDED MATERIAL SEIKO EPSON CORPORATION (JP) 2012-06-14 US disclosed
US-20120147084-A1 INK COMPOSTION, RECORDING METHOD USING THE SAME AND RECORDED MATERIAL SEIKO EPSON CORPORATION (JP) 2012-06-14 US disclosed
US-20120081457-A1 PORPHYRAZINE COLORING MATTER, INK COMPOSITION, RECORDING METHOD, AND COLORED OBJECT NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2012-04-05 US disclosed