Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 3/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL232609 | 0.84 | SLC5A2 (0.35) | SLC5A2SIGMAR1MEN1KMT2ATP53 | |
| SCHEMBL9518703 | 0.83 | CYP4F2 (0.41) | SLC5A2SIGMAR1S1PR3SPHK2SPHK1 | |
| SCHEMBL9520126 | 0.83 | SIGMAR1 (0.35) | SLC5A2SIGMAR1MEN1KMT2ATP53 | |
| SCHEMBL10169200 | 0.81 | ALDH1A1 (0.34) | SLC5A2SIGMAR1MEN1KMT2ATP53 | |
| SCHEMBL9281772 | 0.79 | TDP1 (0.41) | SLC5A2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL6513632 | 0.79 | HTT (0.36) | SLC5A2MEN1KMT2ACYP2C19ALDH1A1 | |
| SCHEMBL15393001 | 0.76 | MAOB (0.33) | SLC5A2MEN1KMT2AALDH1A1HTT | |
| SCHEMBL2280642 | 0.75 | MEN1 (0.58) | SLC5A2MEN1KMT2AALDH1A1HTT | |
| SCHEMBL6517254 | 0.75 | CHRNB4 (0.45) | SLC5A2TSHRALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL5604860 | 0.75 | NCF1 (0.44) | ALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012003482-A2 | HOLE TRANSPORT COMPOSITIONS AND RELATED DEVICES AND METHODS (II) | PLEXTRONICS, INC. (US) | 2012-01-05 | — | — | WO | disclosed |