SCHEMBL10171287

SCHEMBL10171287

CCCON(CC(=O)O)CC(=O)O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BLM P54132 3/20 0.37
PMP22 Q01453 2/20 0.37
HSD17B10 Q99714 2/20 0.37
FFAR3 O14843 2/20 0.36
HDAC3 O15379 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
PLA2G2A P14555 1/20 0.35
TDP1 Q9NUW8 5/20 0.35
EYA2 O00167 1/20 0.35
APP P05067 1/20 0.35
ACE P12821 1/20 0.35
HCAR2 Q8TDS4 1/20 0.34
TSHR P16473 4/20 0.33
LMNA P02545 3/20 0.33
ALDH1A1 P00352 3/20 0.33
ALOX15 P16050 2/20 0.33
KDM4E B2RXH2 1/20 0.33
CHRM2 P08172 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8048010 0.85 BLM (0.42) BLMPMP22HSD17B10TDP1EYA2
SCHEMBL10171416 0.83 PLA2G2A (0.49) BLMHSD17B10PLA2G2ATDP1APP
SCHEMBL7717708 0.81 BLM (0.37) BLMPMP22HSD17B10FFAR3HDAC3
SCHEMBL3338460 0.80 FFAR3 (0.38) BLMPMP22HSD17B10FFAR3HDAC3
SCHEMBL8663088 0.80 FFAR3 (0.38) BLMPMP22HSD17B10FFAR3HDAC3
SCHEMBL9093646 0.80 BLM (0.39) BLMPMP22HSD17B10PLA2G2ATDP1
SCHEMBL9817086 0.78 BLM (0.38) BLMPMP22HSD17B10TDP1EYA2
SCHEMBL158008 0.78 BLM (0.54) BLMPMP22HSD17B10TDP1EYA2
SCHEMBL19209772 0.77 BLM (0.34) BLMPMP22HSD17B10FFAR3HDAC3
SCHEMBL10171563 0.76 CA12 (0.46) HSD17B10TDP1TSHRLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8101325-B2 Azo compound, curable composition, color filter, and method of producing the same FUJIFILM CORPORATION (JP) 2012-01-24 US disclosed
US-20090075188-A1 AZO COMPOUND, CURABLE COMPOSITION, COLOR FILTER, AND METHOD OF PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2009-03-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090075188-A1 AZO COMPOUND, CURABLE COMPOSITION, COLOR FILTER, AND METHOD OF PRODUCING THE SAME CRY1, RB1, CRY2 BLM 1463/4885PMP22 4841/4885HSD17B10 3326/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.