Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 17/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND3 | P30281 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL357418 | 0.94 | ERBB2 (0.45) | ERBB2CYP2C9CYP3A4GPR119CCNT1 | |
| SCHEMBL355058 | 0.92 | GPR119 (0.48) | ERBB2CYP2C9CYP3A4GPR119 | |
| SCHEMBL356179 | 0.87 | CYP3A4 (0.56) | ERBB2CYP2C9CYP3A4GPR119 | |
| SCHEMBL10171992 | 0.85 | GPR119 (0.43) | ERBB2CYP2C9CYP3A4GPR119 | |
| SCHEMBL10172170 | 0.85 | GPR119 (0.45) | ERBB2CYP2C9CYP3A4GPR119 | |
| SCHEMBL355091 | 0.84 | ERBB2 (0.48) | ERBB2CYP2C9CYP3A4GPR119CCNT1 | |
| SCHEMBL10172675 | 0.84 | CYP3A4 (0.48) | ERBB2CYP2C9CYP3A4GPR119 | |
| SCHEMBL10171944 | 0.84 | GPR119 (0.49) | CYP2C9CYP3A4GPR119 | |
| SCHEMBL10171823 | 0.83 | GPR119 (0.44) | ERBB2CYP2C9CYP3A4GPR119 | |
| Hydrochloric Acid SCHEMBL368931 | 0.83 | GPR119 (0.49) | CYP2C9CYP3A4GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120016119-A1 | NOVEL PYRROLO(2,3-d)PYRIMIDINE COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016119-A1 | NOVEL PYRROLO(2,3-d)PYRIMIDINE COMPOUND | GPR119, GPR139, HCAR1 | ERBB2 451/4885CYP2C9 1147/4885CYP3A4 2136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.