Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 2/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | WDR5 | P61964 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | NEK7 | Q8TDX7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10172164 | 0.94 | GPR119 (0.40) | PTK6GPR119KCNH2NEK7 | |
| SCHEMBL10171898 | 0.94 | GPR119 (0.40) | PTK6GPR119KCNH2NEK7 | |
| SCHEMBL10171977 | 0.91 | GPR119 (0.40) | GPR119LRRK2NEK7 | |
| SCHEMBL10171832 | 0.90 | GPR119 (0.39) | GPR119KCNH2NEK7 | |
| Hydrochloric Acid SCHEMBL356215 | 0.90 | GPR119 (0.42) | GPR119NEK7 | |
| SCHEMBL10171796 | 0.89 | GPR119 (0.49) | GPR119NEK7 | |
| SCHEMBL10171855 | 0.89 | GPR119 (0.48) | GPR119NEK7 | |
| SCHEMBL10171894 | 0.86 | GPR119 (0.40) | GPR119KCNH2NEK7 | |
| SCHEMBL10172649 | 0.85 | GPR119 (0.42) | GPR119KCNH2NEK7 | |
| SCHEMBL10171989 | 0.84 | GPR119 (0.41) | GPR119KCNH2NEK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120016119-A1 | NOVEL PYRROLO(2,3-d)PYRIMIDINE COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016119-A1 | NOVEL PYRROLO(2,3-d)PYRIMIDINE COMPOUND | GPR119, GPR139, HCAR1 | PTK6 2572/4885TNKS 3097/4885GPR119 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.