Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.53 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 4/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | NEK7 | Q8TDX7 | 6/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10172671 | 0.92 | GPR119 (0.43) | GPR119BRAFNEK7CYP3A4CYP2C9 | |
| SCHEMBL10172703 | 0.92 | GPR119 (0.46) | GPR119ERBB2BRAFHDAC4NEK7 | |
| SCHEMBL10172695 | 0.92 | GPR119 (0.45) | GPR119ERBB2BRAFHDAC4NEK7 | |
| Hydrochloric Acid SCHEMBL355012 | 0.91 | GPR119 (0.43) | GPR119BRAFNEK7CYP3A4CYP2C9 | |
| SCHEMBL10172645 | 0.91 | GPR119 (0.44) | GPR119ERBB2BRAFHDAC4NEK7 | |
| SCHEMBL356723 | 0.90 | GPR119 (0.45) | GPR119BRAFHDAC4NEK7CYP3A4 | |
| SCHEMBL10172009 | 0.90 | GPR119 (0.51) | GPR119ERBB2BRAFNEK7CYP3A4 | |
| SCHEMBL10171900 | 0.89 | HDAC4 (0.42) | GPR119ERBB2BRAFHDAC4NEK7 | |
| SCHEMBL10171921 | 0.89 | GPR119 (0.49) | GPR119ERBB2BRAFNEK7CYP3A4 | |
| SCHEMBL10171797 | 0.89 | GPR119 (0.49) | GPR119ERBB2BRAFNEK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120016119-A1 | NOVEL PYRROLO(2,3-d)PYRIMIDINE COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016119-A1 | NOVEL PYRROLO(2,3-d)PYRIMIDINE COMPOUND | GPR119, GPR139, HCAR1 | GPR119 1/4885ERBB2 451/4885BRAF 2824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.