Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | GPR119 | Q8TDV5 | 18/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10171802 | 0.87 | CYP3A4 (0.51) | CYP3A4CYP2C9GPR119 | |
| SCHEMBL358043 | 0.84 | CYP3A4 (0.53) | CYP3A4CYP2C9GPR119 | |
| SCHEMBL356930 | 0.84 | CYP3A4 (0.54) | CYP3A4CYP2C9GPR119 | |
| SCHEMBL355582 | 0.83 | CYP3A4 (0.52) | CYP3A4CYP2C9GPR119 | |
| SCHEMBL10171813 | 0.82 | GPR119 (0.66) | CYP3A4CYP2C9GPR119 | |
| SCHEMBL10137715 | 0.82 | GPR119 (0.83) | CYP3A4CYP2C9GPR119 | |
| SCHEMBL356179 | 0.81 | CYP3A4 (0.56) | CYP3A4CYP2C9GPR119 | |
| SCHEMBL10172153 | 0.81 | GPR119 (0.69) | CYP3A4CYP2C9GPR119 | |
| SCHEMBL10172673 | 0.81 | CYP3A4 (0.56) | CYP3A4CYP2C9GPR119 | |
| SCHEMBL12596372 | 0.81 | CYP3A4 (0.78) | CYP3A4CYP2C9GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120016119-A1 | NOVEL PYRROLO(2,3-d)PYRIMIDINE COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016119-A1 | NOVEL PYRROLO(2,3-d)PYRIMIDINE COMPOUND | GPR119, GPR139, HCAR1 | CYP3A4 2136/4885CYP2C9 1147/4885GPR119 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.