Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.61 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | KDR | P35968 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28588190 | 0.98 | ESR1 (0.59) | ESR1TSHRCYP2D6LMNASMN1; SMN2 | |
| SCHEMBL10172838 | 0.95 | ESR1 (0.63) | ESR1TSHRCYP2D6LMNASMN1; SMN2 | |
| SCHEMBL10172875 | 0.88 | ESR1 (0.61) | ESR1TSHRCYP2D6LMNASMN1; SMN2 | |
| SCHEMBL2880231 | 0.86 | ESR1 (0.79) | ESR1TSHRCYP2D6LMNASMN1; SMN2 | |
| SCHEMBL10172853 | 0.85 | TDP1 (0.73) | ESR1LMNASMN1; SMN2MAPK1TDP1 | |
| SCHEMBL10760934 | 0.84 | ESR1 (0.76) | ESR1TSHRCYP2D6LMNASMN1; SMN2 | |
| SCHEMBL8638754 | 0.84 | ESR1 (0.76) | ESR1TSHRCYP2D6LMNASMN1; SMN2 | |
| SCHEMBL9674690 | 0.84 | ESR1 (0.76) | ESR1TSHRCYP2D6LMNASMN1; SMN2 | |
| SCHEMBL1548913 | 0.84 | ESR1 (0.76) | ESR1TSHRCYP2D6LMNASMN1; SMN2 | |
| SCHEMBL8638181 | 0.82 | ESR1 (0.79) | ESR1TSHRCYP2D6LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9200098-B2 | Radiation-sensitive composition and compound | JSR CORPORATION (JP) | 2015-12-01 | — | — | US | disclosed |
| US-9200098-B2 | Radiation-sensitive composition and compound | JSR CORPORATION (JP) | 2015-12-01 | — | — | US | disclosed |
| US-20120164582-A1 | RADIATION-SENSITIVE COMPOSITION AND COMPOUND | JSR CORPORATION (JP) | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120164582-A1 | RADIATION-SENSITIVE COMPOSITION AND COMPOUND | RAD51, RER1, ATP6AP1 | ESR1 282/4885TSHR 1556/4885CYP2D6 1335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.