Gluconolactone

Gluconolactone

SCHEMBL10173017

O=C1OC(CO)[C@@H](O)[C@H](O)C1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 1.00
GBA1 P04062 2/20 1.00
HIF1A Q16665 2/20 0.47
MANBA O00462 2/20 0.47
IDUA P35475 1/20 0.47
THRB P10828 1/20 0.47
GUSB P08236 1/20 0.47
CYP2C19 P33261 1/20 0.42
DNMT1 P26358 1/20 0.38
CTDSP1 Q9GZU7 1/20 0.38
OGA O60502 1/20 0.38
GAA P10253 1/20 0.37
PYGB P11216 2/20 0.37
PYGL P06737 1/20 0.37
PYGM P11217 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Gluconolactone SCHEMBL18465607 1.00 LMNA (1.00) LMNAGBA1HIF1AMANBAIDUA
Gluconolactone SCHEMBL333412 1.00 LMNA (1.00) LMNAGBA1HIF1AMANBAIDUA
Gluconolactone SCHEMBL2466472 1.00 LMNA (1.00) LMNAGBA1HIF1AMANBAIDUA
Gluconolactone SCHEMBL7148519 1.00 LMNA (1.00) LMNAGBA1HIF1AMANBAIDUA
Gluconolactone SCHEMBL17068350 1.00 LMNA (1.00) LMNAGBA1HIF1AMANBAIDUA
Gluconolactone SCHEMBL15631270 1.00 LMNA (1.00) LMNAGBA1HIF1AMANBAIDUA
Gluconolactone SCHEMBL24637666 1.00 LMNA (1.00) LMNAGBA1HIF1AMANBAIDUA
Gluconolactone SCHEMBL15631261 1.00 LMNA (1.00) LMNAGBA1HIF1AMANBAIDUA
Gluconolactone SCHEMBL15631260 1.00 LMNA (1.00) LMNAGBA1HIF1AMANBAIDUA
Gluconolactone SCHEMBL2464302 1.00 LMNA (1.00) LMNAGBA1HIF1AMANBAIDUA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11656159-B2 Composition for preparing biological material having excellent light transmissivity and use of composition RIKEN (JP) 2023-05-23 US disclosed
US-20160305889-A1 METHOD FOR MEASURING CONCENTRATION OF TEST SUBSTANCE, AND DETECTION APPARATUS OSAKA UNIVERSITY (JP) 2016-10-20 US disclosed
US-20160305889-A1 METHOD FOR MEASURING CONCENTRATION OF TEST SUBSTANCE, AND DETECTION APPARATUS OSAKA UNIVERSITY (JP) 2016-10-20 US disclosed
US-20160168183-A1 Conjugates Containing Hydrophilic Spacer Linkers ENDOCYTE INC (US) 2016-06-16 US disclosed
US-9359322-B2 C-linked glucuronide of N-(4-hydroxybenzyl) retinone, analogs thereof, and methods of using the same to inhibit neoplastic cell growth WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2016-06-07 US disclosed
US-9359322-B2 C-linked glucuronide of N-(4-hydroxybenzyl) retinone, analogs thereof, and methods of using the same to inhibit neoplastic cell growth WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2016-06-07 US disclosed
US-9138484-B2 Conjugates containing hydrophilic spacer linkers ENDOCYTE, INC. (US) 2015-09-22 US disclosed
US-20140271474-A1 INHIBITOR PROBES FOR IMAGING SODIUM-GLUCOSE COTRANSPORTERS IN HEALTH AND DISEASE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2014-09-18 US disclosed
US-20140073761-A1 CONJUGATES CONTAINING HYDROPHILIC SPACER LINKERS ENDOCYTE, INC. (US) 2014-03-13 US disclosed
US-20140073761-A1 CONJUGATES CONTAINING HYDROPHILIC SPACER LINKERS ENDOCYTE, INC. (US) 2014-03-13 US disclosed
US-20100323973-A1 CONJUGATES CONTAINING HYDROPHILIC SPACER LINKERS ENDOCTYE, INC. 2010-12-23 US disclosed
US-20090215706-A1 C-LINKED GLUCURONIDE OF N-(4-HYDROXYBENZYL) RETINONE, ANALOGS THEREOF, AND METHOD OF USING THE SAME TO INHIBIT NEOPLASTIC CELL GROWTH THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION 2009-08-27 US disclosed
US-20090133162-A1 Method of increasing plant organ and seed size in a plant FERNANDES MARY 2009-05-21 US disclosed
US-7528114-B2 C-linked glucuronide of N-(4-hydroxybenzyl) retinone, analogs thereof, and method of using the same to inhibit neoplastic cell growth WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2009-05-05 US disclosed
US-7335812-B2 Method of increasing plant organ and seed size in a plant MONSANTO TECHNOLOGY LLC (US) 2008-02-26 US disclosed
US-20070224490-A1 Suspension for the Generation of a Current of Electrons and the Use and the Preparation Thereof JANSSEN CATHARINA P 2007-09-27 US disclosed
US-20070108057-A1 Enzyme immobilization for electroosmotic flow NATIONAL SCIENCE FOUNDATION 2007-05-17 US disclosed
US-7172682-B2 Enzyme immobilization for electroosmotic flow RENSSELAER POLYTECHNIC INSTITUTE (US) 2007-02-06 US disclosed
US-7172682-B2 Enzyme immobilization for electroosmotic flow RENSSELAER POLYTECHNIC INSTITUTE (US) 2007-02-06 US disclosed
US-20070000781-A1 ENZYME IMMOBILIZATION FOR ELECTROOSMOTIC FLOW RENSSELAER POLYTECHNIC INSTITUTE (US) 2007-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070000781-A1 ENZYME IMMOBILIZATION FOR ELECTROOSMOTIC FLOW MGAM, PNKP, AGL LMNA 2979/4885GBA1 1644/4885HIF1A 4115/4885
US-20140271474-A1 INHIBITOR PROBES FOR IMAGING SODIUM-GLUCOSE COTRANSPORTERS IN HEALTH AND DISEASE SLC5A1, SLC5A2, SLC2A4 LMNA 4229/4885GBA1 220/4885HIF1A 992/4885
US-20160168183-A1 Conjugates Containing Hydrophilic Spacer Linkers CD44, HAVCR2, HCAR1 LMNA 903/4885GBA1 309/4885HIF1A 411/4885
US-20090215706-A1 C-LINKED GLUCURONIDE OF N-(4-HYDROXYBENZYL) RETINONE, ANALOGS THEREOF, AND METHOD OF USING THE SAME TO INHIBIT NEOPLASTIC CELL GROWTH UGT2B17, ALDH1A2, UGT2B7 LMNA 1714/4885GBA1 906/4885HIF1A 1802/4885
US-20100323973-A1 CONJUGATES CONTAINING HYDROPHILIC SPACER LINKERS CD44, HAVCR2, HCAR1 LMNA 903/4885GBA1 309/4885HIF1A 411/4885
US-20140073761-A1 CONJUGATES CONTAINING HYDROPHILIC SPACER LINKERS CD44, HAVCR2, HCAR1 LMNA 903/4885GBA1 309/4885HIF1A 411/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.