Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29115527 | 0.92 | TSHR (0.59) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL19125928 | 0.89 | TSHR (0.59) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL3738577 | 0.87 | TSHR (0.62) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL1014645 | 0.87 | TSHR (0.56) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL7799294 | 0.84 | THRB (0.65) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL11583525 | 0.84 | TSHR (0.84) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL14893 | 0.84 | TSHR (0.84) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL19066401 | 0.84 | TSHR (0.84) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL29076714 | 0.84 | TSHR (0.49) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL1083624 | 0.83 | TSHR (0.75) | TSHRTHRBALDH1A1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2271705-A1 | MODIFIED HALOGENATED POLYMER SURFACES | BASF SE (DE) | 2011-01-12 | — | — | EP | disclosed |
| WO-2009130233-A1 | MODIFIED HALOGENATED POLYMER SURFACES | BASF SE (DE) | 2009-10-29 | — | — | WO | disclosed |