Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 5/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29115527 | 0.95 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL31438968 | 0.87 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL1017355 | 0.87 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL19125928 | 0.85 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL1014645 | 0.83 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL8766935 | 0.83 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL3898618 | 0.81 | TSHR (0.58) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL7799294 | 0.81 | THRB (0.65) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL29076714 | 0.81 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9706878 | 0.80 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829254-B2 | Non-magnetic toner, image forming apparatus and process cartridge | RICOH COMPANY, LTD. (JP) | 2010-11-09 | — | — | US | disclosed |
| US-20070218388-A1 | NON-MAGNETIC TONER, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE | RICOH COMPANY, LTD. (JP) | 2007-09-20 | — | — | US | disclosed |