SCHEMBL7799294

SCHEMBL7799294

C=C(C)C(=O)OCCC[SiH2]OCCOCC

nearest known ligand 0.65

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.65
TSHR P16473 5/20 0.50
ALDH1A1 P00352 5/20 0.41
POLB P06746 1/20 0.37
APEX1 P27695 1/20 0.37
HTT P42858 1/20 0.37
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1014645 0.87 TSHR (0.56) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL29115527 0.86 TSHR (0.59) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL29076714 0.84 TSHR (0.49) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL1017355 0.84 TSHR (0.62) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL19125928 0.83 TSHR (0.59) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL29008124 0.83 THRB (0.66) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL31438968 0.81 TSHR (0.62) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL3738577 0.81 TSHR (0.62) THRBTSHRALDH1A1POLBAPEX1
Diethylamine SCHEMBL27862080 0.81 TSHR (0.49) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL2118746 0.80 THRB (0.79) THRBTSHRALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6329456-B1 FOR FORMING A COATING FILM OF HIGH HARDNESS, HEAT RESISTANCE AND WEATHERABILITY MATSUSHITA ELECTRIC WORKS, LTD. (JP) 2001-12-11 US disclosed
US-6090873-A ACRYLATE TERPOLYMER CONTAINING EPOXY AND ALKOXYSILANE GROUPS MATSUSHITA ELECTRIC WORKS, LTD. (JP) 2000-07-18 US disclosed
EP-0822240-A1 COATING RESIN COMPOSITION MATSUSHITA ELECTRIC WORKS, LTD. (JP) 1998-02-04 EP disclosed