SCHEMBL10173639

SCHEMBL10173639

CCCC(NC)C(=O)OC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
ZDHHC7 Q9NXF8 1/20 0.42
TAS1R3 Q7RTX0 5/20 0.41
TAS1R1 Q7RTX1 5/20 0.41
HDAC7 Q8WUI4 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
HDAC9 Q9UKV0 1/20 0.37
HDAC5 Q9UQL6 1/20 0.37
HDAC2 Q92769 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
CHRM1 P11229 1/20 0.36
AKR1A1 P14550 1/20 0.36
CHRM3 P20309 1/20 0.36
HTR2A P28223 1/20 0.36
HTR2C P28335 1/20 0.36
ADRA1A P35348 1/20 0.36
HRH1 P35367 1/20 0.36
DRD3 P35462 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26076486 1.00 CA1 (0.45) CA1CA2ZDHHC7TAS1R3TAS1R1
Hydrochloric Acid SCHEMBL28044611 0.98 CA1 (0.44) CA1CA2ZDHHC7TAS1R3TAS1R1
SCHEMBL13186899 0.85 CA2 (0.42) CA1CA2ZDHHC7TAS1R3TAS1R1
Hydrochloric Acid SCHEMBL28175518 0.83 L3MBTL1 (0.44) CA1CA2HDAC7HDAC8HDAC6
SCHEMBL30639505 0.82 CA1 (0.36) CA1CA2ZDHHC7TAS1R3TAS1R1
SCHEMBL418520 0.82 CA1 (0.36) CA1CA2ZDHHC7TAS1R3TAS1R1
SCHEMBL2734745 0.81
SCHEMBL18235373 0.81
SCHEMBL8035951 0.81
SCHEMBL15499354 0.81 LMNA (0.37) CA1CA2ZDHHC7HDAC7HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023209090-A1 BICYCLIC HETEROAROMATIC COMPOUNDS AND THEIR APPLICATION IN THE TREATMENT OF CANCER ASTRAZENECA AB (SE) 2023-11-02 WO disclosed
EP-3504210-A1 7-SUBSTITUTED SULFONIMIDOYLPURINONE COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF VIRUS INFECTION H. Hoffnabb-La Roche Ag (CH) 2019-07-03 EP disclosed
CN-107835818-A Anthelmintic depsipeptide compounds 梅里亚股份有限公司 2018-03-23 CN disclosed
WO-2018041763-A1 7-SUBSTITUTED SULFONIMIDOYLPURINONE COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF VIRUS INFECTION F. HOFFMANN-LA ROCHE AG (CH) 2018-03-08 WO disclosed