Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | BLM | P54132 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | PLG | P00747 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.48 |
| ▸ | GABRP | O00591 | 1/20 | 0.48 |
| ▸ | GABRD | O14764 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 5-Aminovaleric Acid SCHEMBL20502251 | 0.75 | NFKB1 (0.89) | NFKB1CYP2D6LMNABLMNPSR1 | |
| 5-Aminovaleric Acid SCHEMBL887118 | 0.75 | NFKB1 (1.00) | NFKB1CYP2D6LMNABLMNPSR1 | |
| 5-Aminovaleric Acid SCHEMBL190150 | 0.75 | — | — | |
| Adipic Acid SCHEMBL2537893 | 0.75 | NFKB1 (1.00) | NFKB1CYP2D6LMNABLMNPSR1 | |
| SCHEMBL14645288 | 0.73 | DNM1 (0.42) | LMNATHRBKMT2AALOX15RECQL | |
| Putrescine SCHEMBL28343590 | 0.73 | NFKB1 (0.84) | NFKB1CYP2D6LMNABLMNPSR1 | |
| Aminocaproic Acid SCHEMBL612543 | 0.73 | LMNA (0.90) | NFKB1CYP2D6LMNABLMNPSR1 | |
| SCHEMBL8063170 | 0.73 | GABRR3 (0.36) | NFKB1LMNABLMNPSR1THRB | |
| 5-Aminovaleric Acid SCHEMBL25349504 | 0.73 | — | — | |
| Aminocaproic Acid SCHEMBL21141584 | 0.73 | LMNA (1.00) | NFKB1CYP2D6LMNABLMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120028901-A1 | TFPI INHIBITORS AND METHODS OF USE | BAXTER INTERNATIONAL INC. (US) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028901-A1 | TFPI INHIBITORS AND METHODS OF USE | TFPI, TFPI2, F3 | NFKB1 714/4885CYP2D6 3856/4885LMNA 1445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.